User profiles for "author:J A Cooper"

Jonathan A. Cooper

- Verified email at fhcrc.org - Cited by 49779

John A. Cooper

- Verified email at wustl.edu - Cited by 29813

Ultrawide‐bandgap semiconductors: research opportunities and challenges

JY Tsao, S Chowdhury, MA Hollis… - Advanced Electronic …, 2018 - Wiley Online Library
Abstract Ultrawide‐bandgap (UWBG) semiconductors, with bandgaps significantly wider
than the 3.4 eV of GaN, represent an exciting and challenging new area of research in …

Effects of cytochalasin and phalloidin on actin.

JA Cooper - The Journal of cell biology, 1987 - ncbi.nlm.nih.gov
YTOCHALASINS and phalloidins are two groups of small, naturally occurring organic
molecules that bind to actin and alter its polymerization. They have been widely used to …

Protein-tyrosine kinases

T Hunter, JA Cooper - Annual review of biochemistry, 1985 - annualreviews.org
898 HUNTER & COOPER cleotides had set a precedent, reports of orthophosphate
esterified to tyrosine did not emerge until 1979 (1). Phosphotyrosine (P. Tyr) was first …

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

CKDGen Consortium, KidneyGen Consortium… - Nature, 2011 - nature.com
Blood pressure is a heritable trait influenced by several biological pathways and responsive
to environmental stimuli. Over one billion people worldwide have hypertension (≥ 140 mm …

[HTML][HTML] Risk thresholds for alcohol consumption: combined analysis of individual-participant data for 599 912 current drinkers in 83 prospective studies

AM Wood, S Kaptoge, AS Butterworth, P Willeit… - The Lancet, 2018 - thelancet.com
Background Low-risk limits recommended for alcohol consumption vary substantially across
different national guidelines. To define thresholds associated with lowest risk for all-cause …

Mammalian Ras interacts directly with the serine/threonine kinase Raf

AB Vojtek, SM Hollenberg, JA Cooper - Cell, 1993 - cell.com
We have identified proteins that interact with H-Ras using a two hybrid system screen of a
mouse cDNA library. Approximately 50% of the clones identified encoded portionsof the c …

Daily energy expenditure through the human life course

H Pontzer, Y Yamada, H Sagayama, PN Ainslie… - Science, 2021 - science.org
Total daily energy expenditure (“total expenditure”) reflects daily energy needs and is a
critical variable in human health and physiology, but its trajectory over the life course is …

Siponimod versus placebo in secondary progressive multiple sclerosis (EXPAND): a double-blind, randomised, phase 3 study

L Kappos, A Bar-Or, BAC Cree, RJ Fox, G Giovannoni… - The Lancet, 2018 - thelancet.com
Background No treatment has consistently shown efficacy in slowing disability progression
in patients with secondary progressive multiple sclerosis (SPMS). We assessed the effect of …

Actin, a central player in cell shape and movement

TD Pollard, JA Cooper - science, 2009 - science.org
The protein actin forms filaments that provide cells with mechanical support and driving
forces for movement. Actin contributes to biological processes such as sensing …

[HTML][HTML] Mitogen‐activated protein kinases activate the serine/threonine kinases Mnk1 and Mnk2

AJ Waskiewicz, A Flynn, CG Proud, JA Cooper - The EMBO journal, 1997 - embopress.org
Mitogen‐activated protein (MAP) kinases bind tightly to many of their physiologically
relevant substrates. We have identified a new subfamily of murine serine/threonine kinases …