User profiles for "author:James D Stefaniak"

James D. Stefaniak

University of Cambridge
Verified email at cam.ac.uk
Cited by 718

The neural and neurocomputational bases of recovery from post-stroke aphasia

JD Stefaniak, AD Halai… - Nature Reviews Neurology, 2020 - nature.com
Abstract Language impairment, or aphasia, is a disabling symptom that affects at least one
third of individuals after stroke. Some affected individuals will spontaneously recover partial …

The multidimensional nature of aphasia recovery post-stroke

JD Stefaniak, F Geranmayeh, MA Lambon Ralph - Brain, 2022 - academic.oup.com
Abstract Language is not a single function, but instead results from interactions between
neural representations and computations that can be damaged independently of each other …

[HTML][HTML] Language networks in aphasia and health: A 1000 participant activation likelihood estimation meta-analysis

JD Stefaniak, RSW Alyahya, MAL Ralph - Neuroimage, 2021 - Elsevier
Aphasia recovery post-stroke is classically and most commonly hypothesised to rely on
regions that were not involved in language premorbidly, through 'neurocomputational …

[HTML][HTML] Modifiable and non-modifiable risk factors of dementia on midlife cerebral small vessel disease in cognitively healthy middle-aged adults: the PREVENT …

A Low, MA Prats-Sedano, E McKiernan… - Alzheimer's research & …, 2022 - Springer
Background Considerable overlap exists between the risk factors of dementia and cerebral
small vessel disease (SVD). However, studies remain limited to older cohorts wherein …

In vivo neuroinflammation and cerebral small vessel disease in mild cognitive impairment and Alzheimer's disease

A Low, E Mak, M Malpetti, L Passamonti… - Journal of Neurology …, 2021 - jnnp.bmj.com
Introduction Associations between cerebral small vessel disease (SVD) and inflammation
have been largely examined using peripheral blood markers of inflammation, with few …

[HTML][HTML] Peak width of skeletonized mean diffusivity as a marker of diffuse cerebrovascular damage

A Low, E Mak, JD Stefaniak, M Malpetti… - Frontiers in …, 2020 - frontiersin.org
Background The peak width of skeletonized mean diffusivity (PSMD) has been proposed as
a fully automated imaging marker of relevance to cerebral small vessel disease (SVD). We …

CAIDE dementia risk score relates to severity and progression of cerebral small vessel disease in healthy midlife adults: the PREVENT-Dementia study

A Low, MA Prats-Sedano, JD Stefaniak… - Journal of Neurology …, 2022 - jnnp.bmj.com
Background Markers of cerebrovascular disease are common in dementia, and may be
present before dementia onset. However, their clinical relevance in midlife adults at risk of …

[HTML][HTML] Efficient and effective assessment of deficits and their neural bases in stroke aphasia

AD Halai, BDD Perez, JD Stefaniak, MAL Ralph - Cortex, 2022 - Elsevier
Objective Multi-assessment batteries are necessary for diagnosing and quantifying the
multifaceted deficits observed post-stroke. Extensive batteries are thorough but impractically …

Discontinuation and non-publication of clinical trials in cardiovascular medicine

AJ Roddick, FTS Chan, JD Stefaniak… - International journal of …, 2017 - Elsevier
Background Appropriate dissemination of clinical data is crucial for minimising bias. Despite
this, high rates of study discontinuation and non-publication have been reported among …

Enzyme replacement therapy and white matter hyperintensity progression in Fabry disease

JD Stefaniak, LM Parkes, AR Parry-Jones, GM Potter… - Neurology, 2018 - AAN Enterprises
Objective To explore the association between enzyme replacement therapy (ERT), clinical
characteristics, and the rate of progression of white matter hyperintensities (WMH) in …