Mercury has been a known as a toxic substance for centuries. Whilst the clinical features of
acute mercury poisoning have been well described, chronic low dose exposure to mercury …

Background Antiretroviral chemoprophylaxis before exposure is a promising approach for
the prevention of human immunodeficiency virus (HIV) acquisition. Methods We randomly …

Prospective population based-registers of amyotrophic lateral sclerosis (ALS) have operated
in Europe for over two decades, and have provided important insights into our …

Background Reproductive-age women need effective interventions to prevent the
acquisition of human immunodeficiency virus type 1 (HIV-1) infection. Methods We …

Background Antiretroviral preexposure prophylaxis has been shown to reduce the risk of
human immunodeficiency virus type 1 (HIV-1) infection in some studies, but conflicting …

Background Randomised placebo-controlled trials have shown that daily oral pre-exposure
prophylaxis (PrEP) with tenofovir–emtricitabine reduces the risk of HIV infection. However …

Background Safe and effective long-acting injectable agents for preexposure prophylaxis
(PrEP) for human immunodeficiency virus (HIV) infection are needed to increase the options …

Background and Methods A placebo-controlled trial has shown that treatment with
zidovudine reduces the rate at which human immunodeficiency virus type 1 (HIV-1) is …

Background The effect of HIV pre-exposure prophylaxis (PrEP) depends on uptake,
adherence, and sexual practices. We aimed to assess these factors in a cohort of HIV …

Reports from human case studies indicate a half-life for inorganic mercury in the brain in the
order of years—contradicting older radioisotope studies that estimated half-lives in the order …