Acute symptomatic seizures secondary to autoimmune encephalitis and autoimmune‐associated epilepsy: conceptual definitions
Seizures are a well‐recognized and often prominent manifestation of autoimmune
encephalitic syndromes. Progress in detection of pathogenic neural autoantibodies has led …
encephalitic syndromes. Progress in detection of pathogenic neural autoantibodies has led …
Neuronal surface antibody-mediated autoimmune encephalitis
JJ Linnoila, MR Rosenfeld, J Dalmau - Seminars in neurology, 2014 - thieme-connect.com
In the past few years, many autoimmune encephalitides have been identified, with specific
clinical syndromes and associated antibodies against neuronal surface antigens. There is …
clinical syndromes and associated antibodies against neuronal surface antigens. There is …
Glial fibrillary acidic protein immunoglobulin G as biomarker of autoimmune astrocytopathy: analysis of 102 patients
EP Flanagan, SR Hinson, VA Lennon… - Annals of …, 2017 - Wiley Online Library
Objective A novel autoimmune central nervous system (CNS) disorder with glial fibrillary
acidic protein (GFAP)‐IgG as biomarker was recently characterized. Here, 102 patients with …
acidic protein (GFAP)‐IgG as biomarker was recently characterized. Here, 102 patients with …
[HTML][HTML] Measuring myeloperoxidase activity in biological samples
Background Enzymatic activity measurements of the highly oxidative enzyme
myeloperoxidase (MPO), which is implicated in many diseases, are widely used in the …
myeloperoxidase (MPO), which is implicated in many diseases, are widely used in the …
[HTML][HTML] Autoimmune and paraneoplastic chorea: a review of the literature
K Kyle, Y Bordelon, N Venna, J Linnoila - Frontiers in Neurology, 2022 - frontiersin.org
Autoimmune chorea syndromes represent a vast array of paraneoplastic, parainfectious and
idiopathic disorders. It is increasingly apparent that familiarity with these disorders is …
idiopathic disorders. It is increasingly apparent that familiarity with these disorders is …
[HTML][HTML] Consensus disease definitions for neurologic immune-related adverse events of immune checkpoint inhibitors
Expanding the US Food and Drug Administration–approved indications for immune
checkpoint inhibitors in patients with cancer has resulted in therapeutic success and …
checkpoint inhibitors in patients with cancer has resulted in therapeutic success and …
CSF herpes virus and autoantibody profiles in the evaluation of encephalitis
JJ Linnoila, MJ Binnicker, M Majed… - Neurology …, 2016 - AAN Enterprises
Objective: To report the frequency of coexisting herpes viruses (herpes simplex virus 1 [HSV-
1] or HSV-2, varicella zoster virus, Epstein-Barr virus [EBV], cytomegalovirus, or human …
1] or HSV-2, varicella zoster virus, Epstein-Barr virus [EBV], cytomegalovirus, or human …
Myeloperoxidase–hepatocyte–stellate cell cross talk promotes hepatocyte injury and fibrosis in experimental nonalcoholic steatohepatitis
Abstract Aims: Myeloperoxidase (MPO), a highly oxidative enzyme secreted by leukocytes
has been implicated in human and experimental nonalcoholic steatohepatitis (NASH), but …
has been implicated in human and experimental nonalcoholic steatohepatitis (NASH), but …
Expanded clinical phenotype, oncological associations, and immunopathologic insights of paraneoplastic Kelch-like protein-11 encephalitis
Importance Recognizing the presenting and immunopathological features of Kelch-like
protein-11 immunoglobulin G seropositive (KLHL11 IgG+) patients may aid in early …
protein-11 immunoglobulin G seropositive (KLHL11 IgG+) patients may aid in early …
Mouse model of anti-NMDA receptor post–herpes simplex encephalitis
J Linnoila, B Pulli, T Armangué… - Neurology …, 2018 - AAN Enterprises
Objective To develop an endogenous rodent model of postinfectious anti-NMDA receptor
(NMDAR) encephalitis. Methods Six mice were inoculated intranasally with herpes simplex …
(NMDAR) encephalitis. Methods Six mice were inoculated intranasally with herpes simplex …