Fossils and molecular data are two independent sources of information that should in
principle provide consistent inferences of when evolutionary lineages diverged. Here we …

The global loss of biodiversity continues at an alarming rate. Genomic approaches have
been suggested as a promising tool for conservation practice as scaling up to genome-wide …

In 2007, an association of single nucleotide polymorphisms (SNPs) in the fat mass and
obesity-associated (FTO) gene region with body mass index (BMI) and risk of obesity was …

Background Mathematics anxiety (MA), a state of discomfort associated with performing
mathematical tasks, is thought to affect a notable proportion of the school age population …

Reduced lung function predicts mortality and is key to the diagnosis of chronic obstructive
pulmonary disease (COPD). In a genome-wide association study in 400,102 individuals of …

We studied genes involved in pancreatic β cell function and survival, identifying associations
between SNPs in WFS1 and diabetes risk in UK populations that we replicated in an …

Background Charcot–Marie–Tooth disease (CMT) is a clinically and genetically
heterogeneous group of diseases with approximately 45 different causative genes …

Lung-function impairment underlies chronic obstructive pulmonary disease (COPD) and
predicts mortality. In the largest multi-ancestry genome-wide association meta-analysis of …

Genome-wide association studies have revealed that common noncoding variants in
MTNR1B (encoding melatonin receptor 1B, also known as MT2) increase type 2 diabetes …

Dystonia type 4 (DYT4) was first described in a large family from Heacham in Norfolk with an
autosomal dominantly inherited whispering dysphonia, generalized dystonia, and a …