Epidemiological and cohort study finds no association between COVID-19 and Guillain-Barré syndrome

S Keddie, J Pakpoor, C Mousele, M Pipis, PM Machado… - Brain, 2021 - academic.oup.com
Abstract Reports of Guillain-Barré syndrome (GBS) have emerged during the Coronavirus
disease 2019 (COVID-19) pandemic. This epidemiological and cohort study sought to …

Demyelinating CMT–what's known, what's new and what's in store?

KM Brennan, Y Bai, ME Shy - Neuroscience letters, 2015 - Elsevier
Inherited neuropathies known collectively as Charcot–Marie–Tooth disease are one of the
most common inherited neurological conditions affecting∼ 1 in 2500 people. A …

[HTML][HTML] The neuropathic potential of anti-GM1 autoantibodies is regulated by the local glycolipid environment in mice

KN Greenshields, SK Halstead… - The Journal of …, 2009 - Am Soc Clin Investig
Anti-GM1 ganglioside autoantibodies are used as diagnostic markers for motor axonal
peripheral neuropathies and are believed to be the primary mediators of such diseases …

Lipid arrays identify myelin-derived lipids and lipid complexes as prominent targets for oligoclonal band antibodies in multiple sclerosis

KM Brennan, F Galban-Horcajo, S Rinaldi… - Journal of …, 2011 - Elsevier
The presence of oligoclonal bands of IgG (OCB) in cerebrospinal fluid (CSF) is used to
establish a diagnosis of multiple sclerosis (MS), but their specificity has remained an enigma …

[HTML][HTML] Antibodies to heteromeric glycolipid complexes in Guillain-Barré syndrome

S Rinaldi, KM Brennan, G Kalna, C Walgaard… - Plos one, 2013 - journals.plos.org
Autoantibodies are infrequently detected in the sera of patients with the demyelinating form
of Guillain-Barré syndrome most commonly encountered in the Western world, despite …

Myelin protein zero mutations and the unfolded protein response in Charcot Marie Tooth disease type 1B

Y Bai, X Wu, KM Brennan, DS Wang… - Annals of clinical …, 2018 - Wiley Online Library
Objective To determine the prevalence of MPZ mutations that cause Charcot Marie Tooth
neuropathy type 1B (CMT 1B) and activate the unfolded protein Response (UPR) …

Analysis of lectin binding to glycolipid complexes using combinatorial glycoarrays

S Rinaldi, KM Brennan, CS Goodyear, C O'Leary… - …, 2009 - academic.oup.com
Glycolipids are major components of the plasma membrane, interacting with themselves,
other lipids, and proteins to form an array of heterogeneous domains with diverse biological …

Two recurrent mutations are associated with GNE myopathy in the North of Britain

A Chaouch, KM Brennan, J Hudson… - Journal of Neurology …, 2014 - jnnp.bmj.com
Objective GNE myopathy is a rare recessive myopathy associated with inclusion bodies on
muscle biopsy. The clinical phenotype is associated with distal muscle weakness with …

Reduced neurofilament expression in cutaneous nerve fibers of patients with CMT2E

C Pisciotta, Y Bai, KM Brennan, X Wu, T Grider… - Neurology, 2015 - AAN Enterprises
Objective: To investigate the effects of NEFL Glu396Lys mutation on the expression and
assembly of neurofilaments (NFs) in cutaneous nerve fibers of patients with Charcot-Marie …

Absence of Dystrophin Related Protein-2 disrupts Cajal bands in a patient with Charcot–Marie–Tooth disease

KM Brennan, Y Bai, C Pisciotta, S Wang… - Neuromuscular …, 2015 - Elsevier
Using exome sequencing in an individual with Charcot–Marie–Tooth disease (CMT) we
have identified a mutation in the X-linked dystrophin-related protein 2 (DRP2) gene. A 60 …