Macromolecules with complementary binding sites associate almost stoichiometrically in
solution to form the “intermacromolecular complex”. Studies on intermacromolecular …

Development of neuronal and glial cells and their maintenance are under control of
neurotrophic factors (NTFs). An exogenous administration of NTFs protects extremely …

This paper presents an inkjet printing method for the fabrication of entire microfluidic
multianalyte chemical sensing devices made from paper suitable for quantitative analysis …

Recent stem cell technology provides a strong therapeutic potential not only for acute
ischemic stroke but also for chronic progressive neurodegenerative diseases such as …

Background In a previous phase 3 study in patients with amyotrophic lateral sclerosis (ALS),
edaravone did not show a significant difference in the Revised ALS Functional Rating Scale …

Amyotrophic lateral sclerosis (ALS) has its onset in middle age and is a progressive disorder
characterized by degeneration of motor neurons of the primary motor cortex, brainstem and …

Recent studies have revealed that the adult mammalian brain has the capacity to regenerate
some neurons after various insults. However, the precise mechanism of insult-induced …

Regional changes in the amount of free fatty acids, polyphosphoinositides, and water
content in the cerebral cortex were examined using a middle cerebral artery occlusion …

This paper reports on an inkjet printing method for the fabrication of lateral flow
immunochromatographic devices made from a single piece of filter paper by patterning …

Our objective was to confirm the efficacy and safety of edaravone in amyotrophic lateral
sclerosis (ALS) patients. We conducted a 36-week confirmatory study, consisting of 12-week …