User profiles for "author:Lester Y Leung"

Lester Y. Leung, MD, MSc

Associate Professor of Neurology, Tufts University School of Medicine
Verified email at tuftsmedicalcenter.org
Cited by 1673

Accuracy of prediction instruments for diagnosing large vessel occlusion in individuals with suspected stroke: a systematic review for the 2018 guidelines for the early …

EE Smith, DM Kent, KR Bulsara, LY Leung… - Stroke, 2018 - Am Heart Assoc
Introduction—Endovascular thrombectomy is a highly efficacious treatment for large vessel
occlusion (LVO). LVO prediction instruments, based on stroke signs and symptoms, have …

Effect of dysphagia screening strategies on clinical outcomes after stroke: a systematic review for the 2018 guidelines for the early management of patients with acute …

EE Smith, DM Kent, KR Bulsara, LY Leung… - Stroke, 2018 - Am Heart Assoc
Introduction—Dysphagia screening protocols have been recommended to identify patients
at risk for aspiration. The American Heart Association convened an evidence review …

[HTML][HTML] Benefits and risks of dual versus single antiplatelet therapy for secondary stroke prevention: a systematic review for the 2021 guideline for the prevention of …

DL Brown, DA Levine, K Albright, MK Kapral, LY Leung… - Stroke, 2021 - journals.lww.com
Background: Dual antiplatelet therapy (DAPT) after ischemic stroke or transient ischemic
attack may reduce recurrent stroke but also increase severe bleeding compared with single …

Synthetic cannabis and acute ischemic stroke

ME Bernson-Leung, LY Leung… - Journal of Stroke and …, 2014 - strokejournal.org
An association between marijuana use and stroke has been previously reported. However,
the health risks of newer synthetic cannabinoid compounds are less well known. We …

[HTML][HTML] Large-scale validation of the prediction model risk of bias assessment Tool (PROBAST) using a short form: high risk of bias models show poorer …

E Venema, BS Wessler, JK Paulus, R Salah… - Journal of Clinical …, 2021 - Elsevier
Objective To assess whether the Prediction model Risk Of Bias ASsessment Tool
(PROBAST) and a shorter version of this tool can identify clinical prediction models (CPMs) …

[HTML][HTML] Natural language processing for the identification of silent brain infarcts from neuroimaging reports

S Fu, LY Leung, Y Wang, AO Raulli… - JMIR medical …, 2019 - medinform.jmir.org
Background: Silent brain infarction (SBI) is defined as the presence of 1 or more brain
lesions, presumed to be because of vascular occlusion, found by neuroimaging (magnetic …

Association of silent cerebrovascular disease identified using natural language processing and future ischemic stroke

DM Kent, LY Leung, Y Zhou, PH Luetmer, DF Kallmes… - Neurology, 2021 - AAN Enterprises
Background and Objectives Silent cerebrovascular disease (SCD), comprising silent brain
infarction (SBI) and white matter disease (WMD), is commonly found incidentally on …

Intravenous tPA for acute ischemic stroke in patients with COVID-19

T Carneiro, J Dashkoff, LY Leung… - Journal of Stroke and …, 2020 - Elsevier
Abstract Background/Purpose: Coronavirus disease 2019 (COVID-19) is associated with
increased risk of acute ischemic stroke (AIS), however, there is a paucity of data regarding …

Blood pressure and heart rate measures associated with increased risk of covert brain infarction and worsening leukoaraiosis in older adults

LY Leung, TM Bartz, K Rice, J Floyd… - … , and vascular biology, 2017 - Am Heart Assoc
Objective—In people without previous stroke, covert findings on serial magnetic resonance
imaging (MRI) of incident brain infarcts and worsening leukoaraiosis are associated with …

Ischaemic stroke associated with COVID-19 and racial outcome disparity in North America

AA Dmytriw, K Phan, C Schirmer… - Journal of Neurology …, 2020 - jnnp.bmj.com
A retrospective study from the COVID-19 outbreak in Wuhan, China demonstrated an
incidence of acute ischaemic stroke of approximately 5% in hospitalised patients with severe …