There is no consensus regarding the classification of optic neuritis, and precise diagnostic
criteria are not available. This reality means that the diagnosis of disorders that have optic …

Hsp70 is a highly conserved and inducible heat shock protein that belongs to the HSP70
family of molecular chaperones and plays a central role in protein homeostasis. The main …

During the last 10 years, exosomes, which are small vesicles of 50–200 nm diameter of
endosomal origin, have aroused a great interest in the scientific and clinical community for …

Background. We assessed the diagnostic value of swab cultures by comparing them with
corresponding cultures of percutaneous bone biopsy specimens for patients with diabetic …

In the era of immunotherapies there is an urgent need to implement the use of circulating
biomarkers in clinical practice to facilitate personalized therapy and to predict treatment …

Background: Exosomes, via heat shock protein 70 (HSP70) expressed in their membrane,
are able to interact with the toll-like receptor 2 (TLR2) on myeloid-derived suppressive cells …

Tumors use tryptophan-catabolizing enzymes such as indoleamine 2, 3-dioxygenase (IDO-
1) to induce an immunosuppressive environment. IDO-1 is induced in response to …

An earlier report suggested that actin and myosin I alpha (MMIα), a myosin associated with
endosomes and lysosomes, were involved in the delivery of internalized molecules to …

Invasive ants are amongst the most destructive and widespread invaders across the globe;
they can strongly alter invaded ecosystems and are responsible for the loss of native ant …

Seventeen diabetic patients with moderate to mild foot lesions associated with 20
osteomyelitic bones diagnosed by both bone scan and bone biopsy received rifampicin plus …