This revision of the “ACC/AHA/NASPE Guidelines for Implantation of Cardiac Pacemakers
and Antiarrhythmia Devices” updates the previous versions published in 1984, 1991, 1998 …

The blood–brain barrier (BBB) is a continuous endothelial membrane within brain
microvessels that has sealed cell-to-cell contacts and is sheathed by mural vascular cells …

The blood-brain barrier (BBB) prevents neurotoxic plasma components, blood cells, and
pathogens from entering the brain. At the same time, the BBB regulates transport of …

The online-only Data Supplement is available with this article at http://circ. ahajournals.
org/lookup/suppl/doi: 10.1161/CIR. 0b013e318276ce9b/-/DC1. The online-only …

The blood-brain barrier (BBB) limits entry of blood-derived products, pathogens, and cells
into the brain that is essential for normal neuronal functioning and information processing …

Vascular contributions to dementia and Alzheimer's disease are increasingly recognized,,,,–.
Recent studies have suggested that breakdown of the blood–brain barrier (BBB) is an early …

Background—Dual-chamber (DDDR) pacing preserves AV synchrony and may reduce heart
failure (HF) and atrial fibrillation (AF) compared with ventricular (VVIR) pacing in sinus node …

Vascular contributions to cognitive impairment are increasingly recognized,,,–as shown by
neuropathological,, neuroimaging,,,–, and cerebrospinal fluid biomarker, studies. Moreover …

Objective To determine whether there is a link between hypoglycaemia and mortality among
participants in the Action to Control Cardiovascular Risk in Diabetes (ACCORD) trial. Design …

Excess cellular cholesterol induces apoptosis in macrophages, an event likely to promote
progression of atherosclerosis. The cellular mechanism of cholesterol-induced apoptosis is …