Insular lesionectomy for refractory epilepsy: management and outcome

M Von Lehe, J Wellmer, H Urbach, J Schramm… - Brain, 2009 - academic.oup.com
Surgical treatment of deep-seated insular lesions causing refractory epilepsy is thought to
be difficult due to the complicated accessibility and close proximity of eloquent areas. Here …

Simple and complex dysembryoplastic neuroepithelial tumors (DNT) variants: clinical profile, MRI, and histopathology

AR Campos, H Clusmann, M von Lehe, P Niehusmann… - Neuroradiology, 2009 - Springer
Abstract Introduction Dysembryoplastic neuroepithelial tumors (DNTs) are long-term
epilepsy associated tumors subdivided into simple and complex variants. The purpose of …

Epilepsy, hippocampal sclerosis and febrile seizures linked by common genetic variation around SCN1A

…, BPC Koeleman, A Becker, S Schoch, M Von Lehe… - Brain, 2013 - academic.oup.com
Epilepsy comprises several syndromes, amongst the most common being mesial temporal
lobe epilepsy with hippocampal sclerosis. Seizures in mesial temporal lobe epilepsy with …

Surgery for spinal cord ependymomas: outcome and prognostic factors

A Boström, M von Lehe, W Hartmann, T Pietsch… - …, 2011 - journals.lww.com
BACKGROUND: Spinal cord tumors account for 5% to 10% of all primary central nervous
system tumors. The most common intramedullary neoplasms are ependymomas, composing …

[HTML][HTML] Systems genetics identifies Sestrin 3 as a regulator of a proconvulsant gene network in human epileptic hippocampus

…, TJ O'Brien, S Petrovski, M Von Lehe… - Nature …, 2015 - nature.com
Gene-regulatory network analysis is a powerful approach to elucidate the molecular
processes and pathways underlying complex disease. Here we employ systems genetics …

Rasmussen encephalitis: incidence and course under randomized therapy with tacrolimus or intravenous immunoglobulins

…, R Sassen, S Kuczaty, H Urbach, M von Lehe… - …, 2013 - Wiley Online Library
Purpose: Rasmussen encephalitis (RE) leads to progressive tissue and function loss of one
brain hemisphere and often intractable epilepsy. This is the first randomized prospective …

Tumor recurrence and malignant progression of gangliogliomas

M Majores, M von Lehe, J Fassunke, J Schramm… - Cancer, 2008 - Wiley Online Library
BACKGROUND. Most gangliogliomas (GGs) are benign tumors, but tumor recurrence and
malignant progression are observed in some patients. METHODS. The authors analyzed …

Risks and benefits of invasive epilepsy surgery workup with implanted subdural and depth electrodes

…, CE Elger, H Urbach, H Clusmann, M von Lehe - …, 2012 - Wiley Online Library
Purpose: In patients with pharmacoresistant focal‐onset seizures, invasive presurgical
workup can identify epilepsy surgery options when noninvasive workup has failed. Yet, the …

Insular gliomas: the case for surgical management

M Simon, G Neuloh, M von Lehe, B Meyer… - Journal of …, 2009 - thejns.org
Object Treatment for insular (paralimbic) gliomas is controversial. In this report the authors
summarize their experience with microsurgical resection of insular tumors. Methods The …

Pediatric functional hemispherectomy: outcome in 92 patients

…, S Kuczaty, R Sassen, CE Elger, M Von Lehe - Acta …, 2012 - Springer
Background The revival of epilepsy surgery after the introduction of modern presurgical
evaluation procedures has led to an increase in hemispherectomy or hemispherotomy …