Cushing's disease requires accurate diagnosis, careful treatment selection, and long-term
management to optimise patient outcomes. The Pituitary Society convened a consensus …

Executive summary Traumatic brain injury (TBI) has the highest incidence of all common
neurological disorders, and poses a substantial public health burden. TBI is increasingly …

Abstract The 13th Acromegaly Consensus Conference was held in November 2019 in Fort
Lauderdale, Florida, and comprised acromegaly experts including endocrinologists and …

We previously reported a syndrome of severe hyperinsulinemia and early-onset
hypertension in three patients with dominant-negative mutations in the nuclear hormone …

Prenatal androgens have important organizing effects on brain development and future
behavior. The second-to-fourth digit length ratio (2D: 4D) has been proposed as a marker of …

Thyroid hormones exert their effects through alpha (TRα1) and beta (TRβ1 and TRβ2)
receptors. Here we describe a child with classic features of hypothyroidism (growth …

Thyroid function tests (TFTs) are amongst the most commonly requested laboratory
investigations in both primary and secondary care. Fortunately, most TFTs are …

Selenium, a trace element that is fundamental to human health, is incorporated into some
proteins as selenocysteine (Sec), generating a family of selenoproteins. Sec incorporation is …

The management of primary hypothyroidism with levothyroxine (L‐T4) is simple, effective
and safe, and most patients report improved well‐being on initiation of treatment. However …

Risk taking is central to human activity. Consequently, it lies at the focal point of behavioral
sciences such as neuroscience, economics, and finance. Many influential models from these …