Since the term “lacune” was adopted in the 1800s to describe infarctions from cerebral small
vessels, their underlying pathophysiological basis remained obscure until the 1960s when …

Background: Microvascular brain injury, typically measured by extent of white matter
hyperintensity (WMH) on MRI, is an important contributor to cognitive impairment in the …

Background and Purpose—White-matter hyperintensities (WMHs) detected by magnetic
resonance imaging are thought to represent the effects of cerebral small-vessel disease and …

Lacunar strokes are appropriately named for their ability to cavitate and form ponds or “little
lakes”(Latin: lacune-ae meaning pond or pit is a diminutive form of lacus meaning lake) …

Importance Cerebral amyloid angiopathy (CAA) is characteristically associated with
magnetic resonance imaging (MRI) biomarkers of small vessel brain injury, including strictly …

Objective: To investigate whether the topography of dilated perivascular spaces (DPVS)
corresponds with markers of particular small-vessel diseases such as cerebral amyloid …

Objective: To gain insight into different cerebral amyloid angiopathy (CAA) phenotypes and
mechanisms, we investigated cortical superficial siderosis (CSS), a new imaging marker of …

Objective Cerebral amyloid angiopathy (CAA) is caused by cerebrovascular deposition of β‐
amyloid fragments leading to cerebrovascular dysfunction and other brain injuries. This …

Objectives: To determine whether small diffusion-weighted imaging (DWI) lesions occur
beyond the acute posthemorrhage time window in patients with intracerebral hemorrhage …

Opinion statement Cerebellar masses are a heterogenous group of conditions that can
cause compression of the aqueduct or fourth ventricle, resulting in obstructive …