Multiple system atrophy (MSA) is a sporadic neurodegenerative disorder that encompasses
olivopontocerebellar atrophy (OPCA), striatonigral degeneration (SND) and Shy–Drager …

Transactivation response (TAR) DNA‐binding protein of Mr 43 kDa (TDP‐43) is a major
component of the tau‐negative and ubiquitin‐positive inclusions that characterize …

Ubiquitin-positive tau-negative neuronal cytoplasmic inclusions and dystrophic neurites are
common pathological features in frontotemporal lobar degeneration (FTLD) with or without …

Intracellular accumulation of abnormal proteins with conformational changes is the defining
neuropathological feature of neurodegenerative diseases. The pathogenic proteins that …

The ordered assembly of tau protein into filaments characterizes several neurodegenerative
diseases, which are called tauopathies. It was previously reported that, by cryo-electron …

There are numerous observations confirming that microglia expressing major
histocompatibility complex (MHC) class II molecules are associated with the central nervous …

Objective TAR DNA‐binding protein of 43kDa (TDP‐43) is deposited as cytoplasmic and
intranuclear inclusions in brains of patients with frontotemporal lobar degeneration with …

We assessed the clinicopathological features of 92 patients with primary Sjögren's
syndrome-associated neuropathy (76 women, 16 men, 54.7 years, age at onset). The …

TDP-43 is the major component protein of ubiquitin-positive inclusions in brains of patients
with frontotemporal lobar degeneration (FTLD-TDP) or amyotrophic lateral sclerosis (ALS) …

Synucleinopathies, which include multiple system atrophy (MSA), Parkinson's disease,
Parkinson's disease with dementia and dementia with Lewy bodies (DLB), are human …