Defining secondary progressive multiple sclerosis
J Lorscheider, K Buzzard, V Jokubaitis, T Spelman… - Brain, 2016 - academic.oup.com
A number of studies have been conducted with the onset of secondary progressive multiple
sclerosis as an inclusion criterion or an outcome of interest. However, a standardized …
sclerosis as an inclusion criterion or an outcome of interest. However, a standardized …
[HTML][HTML] Geographical variations in sex ratio trends over time in multiple sclerosis
Background A female/male (F/M) ratio increase over time in multiple sclerosis (MS) patients
was demonstrated in many countries around the world. So far, a direct comparison of sex …
was demonstrated in many countries around the world. So far, a direct comparison of sex …
Predictors and dynamics of postpartum relapses in women with multiple sclerosis
SE Hughes, T Spelman, OM Gray… - Multiple Sclerosis …, 2014 - journals.sagepub.com
Background: Several studies have shown that pregnancy reduces multiple sclerosis (MS)
relapses, which increase in the early postpartum period. Postpartum relapse risk has been …
relapses, which increase in the early postpartum period. Postpartum relapse risk has been …
Predictors of long‐term disability accrual in relapse‐onset multiple sclerosis
VG Jokubaitis, T Spelman, T Kalincik… - Annals of …, 2016 - Wiley Online Library
Objective To identify predictors of 10‐year Expanded Disability Status Scale (EDSS) change
after treatment initiation in patients with relapse‐onset multiple sclerosis. Methods Using …
after treatment initiation in patients with relapse‐onset multiple sclerosis. Methods Using …
Sex as a determinant of relapse incidence and progressive course of multiple sclerosis
The aim of this work was to evaluate sex differences in the incidence of multiple sclerosis
relapses; assess the relationship between sex and primary progressive disease course; and …
relapses; assess the relationship between sex and primary progressive disease course; and …
[HTML][HTML] Male sex is independently associated with faster disability accumulation in relapse-onset MS but not in primary progressive MS
Background Multiple Sclerosis is more common in women than men and females have more
relapses than men. In a large international cohort we have evaluated the effect of gender on …
relapses than men. In a large international cohort we have evaluated the effect of gender on …
Towards personalized therapy for multiple sclerosis: prediction of individual treatment response
Timely initiation of effective therapy is crucial for preventing disability in multiple sclerosis;
however, treatment response varies greatly among patients. Comprehensive predictive …
however, treatment response varies greatly among patients. Comprehensive predictive …
Effect of disease-modifying therapy on disability in relapsing-remitting multiple sclerosis over 15 years
Objective To test the hypothesis that immunotherapy prevents long-term disability in
relapsing-remitting multiple sclerosis (MS), we modeled disability outcomes in 14,717 …
relapsing-remitting multiple sclerosis (MS), we modeled disability outcomes in 14,717 …
Higher latitude is significantly associated with an earlier age of disease onset in multiple sclerosis
C Tao, S Simpson, I Van Der Mei, L Blizzard… - Journal of Neurology …, 2016 - jnnp.bmj.com
Background Age at onset (AAO) in multiple sclerosis (MS) is an important marker of disease
severity and may have prognostic significance. Understanding what factors can influence …
severity and may have prognostic significance. Understanding what factors can influence …
Risk of relapse phenotype recurrence in multiple sclerosis
T Kalincik, K Buzzard, V Jokubaitis… - Multiple Sclerosis …, 2014 - journals.sagepub.com
Objectives: The aim was to analyse risk of relapse phenotype recurrence in multiple
sclerosis and to characterise the effect of demographic and clinical features on this …
sclerosis and to characterise the effect of demographic and clinical features on this …