User profiles for "author:Marios Yiannakas"

Marios C. Yiannakas

UCL
Verified email at ucl.ac.uk
Cited by 2679

Generic acquisition protocol for quantitative MRI of the spinal cord

J Cohen-Adad, E Alonso-Ortiz, M Abramovic… - Nature protocols, 2021 - nature.com
Quantitative spinal cord (SC) magnetic resonance imaging (MRI) presents many challenges,
including a lack of standardized imaging protocols. Here we present a prospectively …

Neurite dispersion: a new marker of multiple sclerosis spinal cord pathology?

F Grussu, T Schneider, C Tur, RL Yates… - Annals of clinical …, 2017 - Wiley Online Library
Objective Conventional magnetic resonance imaging (MRI) of the multiple sclerosis spinal
cord is limited by low specificity regarding the underlying pathological processes, and new …

[HTML][HTML] Phenytoin for neuroprotection in patients with acute optic neuritis: a randomised, placebo-controlled, phase 2 trial

R Raftopoulos, SJ Hickman, A Toosy… - The Lancet …, 2016 - thelancet.com
Background Acute demyelinating optic neuritis, a common feature of multiple sclerosis, can
damage vision through neurodegeneration in the optic nerve and in its fibres in the retina …

Automatic segmentation of the spinal cord and intramedullary multiple sclerosis lesions with convolutional neural networks

C Gros, B De Leener, A Badji, J Maranzano, D Eden… - Neuroimage, 2019 - Elsevier
The spinal cord is frequently affected by atrophy and/or lesions in multiple sclerosis (MS)
patients. Segmentation of the spinal cord and lesions from MRI data provides measures of …

[HTML][HTML] Spinal cord grey matter segmentation challenge

F Prados, J Ashburner, C Blaiotta, T Brosch… - Neuroimage, 2017 - Elsevier
An important image processing step in spinal cord magnetic resonance imaging is the ability
to reliably and accurately segment grey and white matter for tissue specific analysis. There …

Cervical cord lesion load is associated with disability independently from atrophy in MS

H Kearney, DR Altmann, RS Samson, MC Yiannakas… - Neurology, 2015 - AAN Enterprises
Objective: To investigate whether spinal cord (SC) lesion load, when quantified on axial
images with high in-plane resolution, is associated with disability in multiple sclerosis (MS) …

Spatial distribution of multiple sclerosis lesions in the cervical spinal cord

D Eden, C Gros, A Badji, SM Dupont, B De Leener… - Brain, 2019 - academic.oup.com
Spinal cord lesions detected on MRI hold important diagnostic and prognostic value for
multiple sclerosis. Previous attempts to correlate lesion burden with clinical status have had …

[HTML][HTML] Open-access quantitative MRI data of the spinal cord and reproducibility across participants, sites and manufacturers

J Cohen-Adad, E Alonso-Ortiz, M Abramovic, C Arneitz… - Scientific Data, 2021 - nature.com
In a companion paper by Cohen-Adad et al. we introduce the spine generic quantitative MRI
protocol that provides valuable metrics for assessing spinal cord macrostructural and …

Improved MRI quantification of spinal cord atrophy in multiple sclerosis

H Kearney, MC Yiannakas… - Journal of magnetic …, 2014 - Wiley Online Library
Purpose To identify an improved method for measuring spinal cord cross‐sectional area
(CSA) using magnetic resonance imaging (MRI) in multiple sclerosis (MS). Materials and …

Value of the central vein sign at 3T to differentiate MS from seropositive NMOSD

R Cortese, L Magnollay, C Tur, K Abdel-Aziz, A Jacob… - Neurology, 2018 - AAN Enterprises
Objective To assess the value of the central vein sign (CVS) on a clinical 3T scanner to
distinguish between multiple sclerosis (MS) and neuromyelitis optica spectrum disorder …