Study of motor asymmetry in ALS indicates an effect of limb dominance on onset and spread of weakness, and an important role for upper motor neurons
MS Devine, MC Kiernan, S Heggie… - … Lateral Sclerosis and …, 2014 - Taylor & Francis
In amyotrophic lateral sclerosis (ALS), onset and spread of upper motor neuron (UMN) and
lower motor neuron (LMN) dysfunction is typically asymmetric. Our aim was to investigate …
lower motor neuron (LMN) dysfunction is typically asymmetric. Our aim was to investigate …
Targeted assessment of lower motor neuron burden is associated with survival in amyotrophic lateral sclerosis
MS Devine, E Ballard, P O'Rourke… - … Lateral Sclerosis and …, 2016 - Taylor & Francis
Estimating survival in amyotrophic lateral sclerosis (ALS) is challenging due to
heterogeneity in clinical features of disease and a lack of suitable markers that predict …
heterogeneity in clinical features of disease and a lack of suitable markers that predict …
[HTML][HTML] Exposing asymmetric gray matter vulnerability in amyotrophic lateral sclerosis
MS Devine, K Pannek, A Coulthard, PA McCombe… - NeuroImage: Clinical, 2015 - Elsevier
Limb weakness in amyotrophic lateral sclerosis (ALS) is typically asymmetric. Previous
studies have identified an effect of limb dominance on onset and spread of weakness …
studies have identified an effect of limb dominance on onset and spread of weakness …
The relationship between limb dominance, disease lateralization and spread of weakness in amyotrophic lateral sclerosis (ALS)
MS Devine, H Woodhouse, PA McCombe… - … Lateral Sclerosis and …, 2013 - Taylor & Francis
There was a novel suggestion that right-dominant individuals with ALS starting in a non-
dominant limb (ie left UL or LL) were more likely to show ipsilateral spread (Table I). This …
dominant limb (ie left UL or LL) were more likely to show ipsilateral spread (Table I). This …
Unraveling Shared Pathways: A Comprehensive Systematic Review of Common Fiber Tracts in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia using …
ARS Alruwaili, MS Devine, P Mccombe - medRxiv, 2023 - medrxiv.org
This systematic review evaluated MRI studies of fibre tract abnormalities in patients with
amyotrophic lateral sclerosis (ALS) and/or fronto-temporal dementia (FTD). After searching 5 …
amyotrophic lateral sclerosis (ALS) and/or fronto-temporal dementia (FTD). After searching 5 …
A developmental perspective on bulbar involvement in amyotrophic lateral sclerosis
MS Devine, A Farrell, H Woodhouse… - … Lateral Sclerosis and …, 2013 - Taylor & Francis
A developmental perspective on bulbar ALS 639 clinical phenotypes, but most prominently
and consistently in patients with UMN-predominant bulbar signs. In general, patients with …
and consistently in patients with UMN-predominant bulbar signs. In general, patients with …
Incidence of hippocampal metastases in non‐small‐cell lung cancer
S Ly, M Lehman, H Liu, C Hukins… - Journal of Medical …, 2020 - Wiley Online Library
Objectives Patients with locally advanced non‐small‐cell lung cancer (LA‐NSCLC) develop
brain metastases in 25–50% of cases during the course of their disease. Data on the …
brain metastases in 25–50% of cases during the course of their disease. Data on the …
Assessing the upper motor neurone: novel UMN biomarkers are needed for clinical trials
RD Henderson, MS Devine - Journal of Neurology, Neurosurgery & …, 2022 - jnnp.bmj.com
The paper by Nitert provides a valuable contribution regarding the importance of the upper
motor neuron (UMN) as a potential disease biomarker of amyotrophic lateral sclerosis (ALS) …
motor neuron (UMN) as a potential disease biomarker of amyotrophic lateral sclerosis (ALS) …