Chemotherapy‐induced peripheral neuropathy (CIPN) is a common dose‐limiting side effect
experienced by patients receiving treatment for cancer. Approximately 30 to 40% of patients …

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease affecting motor neurons
and other neuronal cells, leading to severe disability and eventually death from ventilatory …

Abstract Paclitaxel (Brand name Taxol) is widely used in the treatment of common cancers
like breast, ovarian and lung cancer. Although highly effective in blocking tumor progression …

Strengthening of synaptic connections following coincident pre-and postsynaptic activity was
proposed by Hebb as a cellular mechanism for learning. Contemporary models assume that …

Cisplatin is a platinum-based chemotherapeutic agent that induces peripheral neuropathy in
30% of patients. Peripheral neuropathy is the dose limiting side effect, which has no …

Post-surgical neuropathies are usually attributed to mechanical factors, such as
compression, stretch, contusion or transection. The role of inflammatory mechanisms in …

Importance Neurological complications are an increasingly recognized consequence of the
use of anti–programmed death 1 (PD-1) antibodies in the treatment of solid-organ tumors …

Functional loss of TDP-43, an RNA binding protein genetically and pathologically linked to
amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), leads to the …

Purpose Given that the clinical course of oxaliplatin-induced neuropathy is not well defined,
the current study was performed to better understand clinical parameters associated with its …

Action potentials are the end product of synaptic integration, a process influenced by resting
and active neuronal membrane properties. Diversity in these properties contributes to …