User profiles for "author:Nazia Karsan"
Nazia KarsanKing's College London Verified email at kcl.ac.uk Cited by 1176 |
Biological insights from the premonitory symptoms of migraine
N Karsan, PJ Goadsby - Nature Reviews Neurology, 2018 - nature.com
Migraine is a common neurological disorder with a diverse clinical phenotype that
comprises more than just head pain. Premonitory (prodromal) symptoms can start hours to …
comprises more than just head pain. Premonitory (prodromal) symptoms can start hours to …
Calcitonin gene-related peptide and migraine
N Karsan, PJ Goadsby - Current opinion in neurology, 2015 - journals.lww.com
This article highlights the evidence behind the role of CGRP in migraine and the state of
CGRP-based mechanism treatment development. We present a summary of the evidence …
CGRP-based mechanism treatment development. We present a summary of the evidence …
The migraine premonitory phase
N Karsan, P Bose, PJ Goadsby - CONTINUUM: Lifelong Learning …, 2018 - journals.lww.com
PURPOSE OF REVIEW The premonitory phase of migraine is defined as the presence of
nonpainful symptomatology occurring hours to days before the onset of headache …
nonpainful symptomatology occurring hours to days before the onset of headache …
Acid‐sensing ion channel 1: A novel therapeutic target for migraine with aura
PR Holland, S Akerman, AP Andreou… - Annals of …, 2012 - Wiley Online Library
Objective: Migraine with aura is a severe debilitating neurological disorder with few
relatively specific therapeutic options. Methods: We used amiloride, a blocker of epithelial …
relatively specific therapeutic options. Methods: We used amiloride, a blocker of epithelial …
Nitroglycerine triggers triptan-responsive cranial allodynia and trigeminal neuronal hypersensitivity
S Akerman, N Karsan, P Bose, JR Hoffmann… - Brain, 2019 - academic.oup.com
Cranial allodynia associated with spontaneous migraine is reported as either responsive to
triptan treatment or to be predictive of lack of triptan efficacy. These conflicting results …
triptan treatment or to be predictive of lack of triptan efficacy. These conflicting results …
[HTML][HTML] Are some patient-perceived migraine triggers simply early manifestations of the attack?
N Karsan, P Bose, J Newman, PJ Goadsby - Journal of Neurology, 2021 - Springer
Objective To study the agreement between self-reported trigger factors and early
premonitory symptoms amongst a group of migraineurs in both spontaneous and …
premonitory symptoms amongst a group of migraineurs in both spontaneous and …
[HTML][HTML] Migraine is more than just headache: is the link to chronic fatigue and mood disorders simply due to shared biological systems?
N Karsan, PJ Goadsby - Frontiers in Human Neuroscience, 2021 - frontiersin.org
Migraine is a symptomatically heterogeneous condition, of which headache is just one
manifestation. Migraine is a disorder of altered sensory thresholding, with hypersensitivity …
manifestation. Migraine is a disorder of altered sensory thresholding, with hypersensitivity …
Headache and non-headache symptoms provoked by nitroglycerin in migraineurs: a human pharmacological triggering study
N Karsan, PR Bose, C Thompson, J Newman… - …, 2020 - journals.sagepub.com
Background Studying a spontaneous migraine attack is challenging, particularly the earliest
components. Nitroglycerin is a potent, reliable and reproducible migraine trigger of the …
components. Nitroglycerin is a potent, reliable and reproducible migraine trigger of the …
[HTML][HTML] New oral drugs for migraine
N Karsan, PJ Goadsby - CNS drugs, 2022 - Springer
Migraine is a common and disabling neurological disorder, with several manifestations, of
which pain is just one. Despite its worldwide prevalence, there remains a paucity of targeted …
which pain is just one. Despite its worldwide prevalence, there remains a paucity of targeted …
[HTML][HTML] Molecular mechanisms of migraine: Nitric oxide synthase and neuropeptides
N Karsan, H Gosalia, PJ Goadsby - International Journal of Molecular …, 2023 - mdpi.com
Migraine is a common condition with disabling attacks that burdens people in the prime of
their working lives. Despite years of research into migraine pathophysiology and …
their working lives. Despite years of research into migraine pathophysiology and …