Migraine is a common neurological disorder with a diverse clinical phenotype that
comprises more than just head pain. Premonitory (prodromal) symptoms can start hours to …

This article highlights the evidence behind the role of CGRP in migraine and the state of
CGRP-based mechanism treatment development. We present a summary of the evidence …

PURPOSE OF REVIEW The premonitory phase of migraine is defined as the presence of
nonpainful symptomatology occurring hours to days before the onset of headache …

Objective: Migraine with aura is a severe debilitating neurological disorder with few
relatively specific therapeutic options. Methods: We used amiloride, a blocker of epithelial …

Cranial allodynia associated with spontaneous migraine is reported as either responsive to
triptan treatment or to be predictive of lack of triptan efficacy. These conflicting results …

Objective To study the agreement between self-reported trigger factors and early
premonitory symptoms amongst a group of migraineurs in both spontaneous and …

Migraine is a symptomatically heterogeneous condition, of which headache is just one
manifestation. Migraine is a disorder of altered sensory thresholding, with hypersensitivity …

Background Studying a spontaneous migraine attack is challenging, particularly the earliest
components. Nitroglycerin is a potent, reliable and reproducible migraine trigger of the …

Migraine is a common and disabling neurological disorder, with several manifestations, of
which pain is just one. Despite its worldwide prevalence, there remains a paucity of targeted …

Migraine is a common condition with disabling attacks that burdens people in the prime of
their working lives. Despite years of research into migraine pathophysiology and …