Background Control genes, which are often referred to as housekeeping genes, are
frequently used to normalise mRNA levels between different samples. However, the …

Individual variation in fetal hemoglobin (HbF, α2γ2) response underlies the remarkable
diversity in phenotypic severity of sickle cell disease and β thalassemia. HbF levels and HbF …

Background Chronic cluster headache (CH) is a debilitating disorder for which few well-
controlled studies demonstrate effectiveness of available therapies. Non-invasive vagus …

Background Clinical observations and results from recent studies support the use of non-
invasive vagus nerve stimulation (nVNS) for treating cluster headache (CH) attacks. This …

A quantitative trait locus (QTL) controlling HbF levels has previously been mapped to
chromosome 6q23 in an Asian-Indian kindred with β thalassemia and heterocellular …

Introduction Non-invasive vagus nerve stimulation (nVNS; gammaCore®) has the potential
to prevent migraine days in patients with migraine on the basis of mechanistic rationale and …

Amitriptyline. One systematic review and three small, short duration randomized controlled
trials (RCTs) found that amitriptyline reduced the duration and frequency of chronic tension …

Objective This study was undertaken to identify susceptibility loci for cluster headache and
obtain insights into relevant disease pathways. Methods We carried out a genome‐wide …

Common sequence variants situated between the HBS1L and MYB genes on chromosome
6q23. 3 (HMIP) influence the proportion of F cells (erythrocytes that carry measurable …

There has been an apparent resistance amongst mainstream investors to integrate the risk
of stranded assets into investment decisions. This paper considers if the structure of the …