The behavioural/dysexecutive variant of Alzheimer's disease: clinical, neuroimaging and pathological features
R Ossenkoppele, YAL Pijnenburg, DC Perry… - Brain, 2015 - academic.oup.com
A 'frontal variant of Alzheimer's disease'has been described in patients with predominant
behavioural or dysexecutive deficits caused by Alzheimer's disease pathology. The …
behavioural or dysexecutive deficits caused by Alzheimer's disease pathology. The …
The identification of cognitive subtypes in Alzheimer's disease dementia using latent class analysis
NME Scheltens, F Galindo-Garre… - Journal of Neurology …, 2016 - jnnp.bmj.com
Objective Alzheimer's disease (AD) is a heterogeneous disorder with complex underlying
neuropathology that is still not completely understood. For better understanding of this …
neuropathology that is still not completely understood. For better understanding of this …
Cognitive subtypes of probable Alzheimer's disease robustly identified in four cohorts
Abstract Introduction Patients with Alzheimer's disease (AD) show heterogeneity in profile of
cognitive impairment. We aimed to identify cognitive subtypes in four large AD cohorts using …
cognitive impairment. We aimed to identify cognitive subtypes in four large AD cohorts using …
[HTML][HTML] Hypometabolism of the posterior cingulate cortex is not restricted to Alzheimer's disease
NME Scheltens, K van der Weijden, SM Adriaanse… - NeuroImage: Clinical, 2018 - Elsevier
When differential diagnosis of dementia includes both Alzheimer's disease (AD) and the
behavioural variant of frontotemporal dementia (bvFTD), distribution of cerebral glucose …
behavioural variant of frontotemporal dementia (bvFTD), distribution of cerebral glucose …
Prominent non-memory deficits in Alzheimer's disease are associated with faster disease progression
NME Scheltens, BM Tijms… - Journal of …, 2018 - content.iospress.com
Background: Alzheimer's disease (AD) is a heterogeneous disorder. Objective: To
investigate whether cognitive AD subtypes are associated with different rates of disease …
investigate whether cognitive AD subtypes are associated with different rates of disease …
Exploring effects of Souvenaid on cerebral glucose metabolism in Alzheimer's disease
NME Scheltens, CT Briels, M Yaqub… - … Research & Clinical …, 2019 - Wiley Online Library
Introduction Alzheimer's disease (AD) is associated with synapse loss. Souvenaid,
containing the specific nutrient combination Fortasyn Connect, was designed to improve …
containing the specific nutrient combination Fortasyn Connect, was designed to improve …
[HTML][HTML] Design of the NL-ENIGMA study: Exploring the effect of Souvenaid on cerebral glucose metabolism in early Alzheimer's disease
NME Scheltens, IS Kuyper, R Boellaard… - Alzheimer's & Dementia …, 2016 - Elsevier
Introduction Alzheimer's disease is associated with early synaptic loss. Specific nutrients are
known to be rate limiting for synapse formation. Studies have shown that administering …
known to be rate limiting for synapse formation. Studies have shown that administering …
[CITATION][C] [O3–06–04]: PROMINENT NON‐MEMORY DEFICITS IN AD ARE ASSOCIATED WITH A FASTER DISEASE PROGRESSION
WM van der Flier, NME Scheltens… - Alzheimer's & …, 2017 - Wiley Online Library
Background There is considerable heterogeneity in clinical manifestation and rate of decline
among patients with Alzheimer's disease (AD). We previously identified two distinct cognitive …
among patients with Alzheimer's disease (AD). We previously identified two distinct cognitive …
[CITATION][C] P2‐016: EXPLORING THE EFFECT OF SOUVENAID ON CEREBRAL GLUCOSE METABOLISM IN EARLY ALZHEIMER'S DISEASE
CT Briels, NME Scheltens, MM Yaqub… - Alzheimer's & …, 2019 - Wiley Online Library
Background Alzheimer's disease (AD) is associated with synaptic loss. Souvenaid,
containing the specific nutrient combination Fortasyn Connect, was designed to improve …
containing the specific nutrient combination Fortasyn Connect, was designed to improve …
[CITATION][C] IC‐02‐03: Hypometabolism of the posterior cingulate cortex is not restricted to Alzheimer's disease
NME Scheltens, S Adriaanse, PP Oomen… - Alzheimer's & …, 2015 - Wiley Online Library
Background Hypometabolism of the posterior cingulate cortex (PCC) is associated with
Alzheimer's disease (AD). PCC vulnerability, however, could also be present in other …
Alzheimer's disease (AD). PCC vulnerability, however, could also be present in other …