Inositol phospholipids have long been known to have an important regulatory role in cell
physiology. The repertoire of cellular processes known to be directly or indirectly controlled …

Phosphorylated products of phosphatidylinositol play critical roles in the regulation of
membrane traffic, in addition to their classical roles as second messengers in signal …

Dynamin, the founding member of a family of dynamin-like proteins (DLPs) implicated in
membrane remodelling, has a critical role in endocytic membrane fission events. The use of …

Synapsin I (protein I) is a neuron-specific phosphoprotein, which is a substrate for cAMP-
dependent and Ca/calmodulin-dependent protein kinases. In two accompanying studies (De …

Protein interactions form a network whose structure drives cellular function and whose
organization informs biological inquiry. Using high-throughput affinity-purification mass …

Ubiquitination is a post-translation modification in which ubiquitin chains or single ubiquitin
molecules are appended to target proteins, giving rise to poly-or monoubiquitination …

SYNAPTOJANIN is a nerve terminal protein of relative molecular mass 145,000 which
appears to participate with dynamin in synaptic vesicle recycling1, 2. The central region of …

Synapsin I (formerly referred to as protein I) is the collective name for two almost identical
phosphoproteins, synapsin Ia and synapsin Ib (protein Ia and protein Ib), present in the …

During endocytosis, clathrin and the clathrin adaptor protein AP-2, assisted by a variety of
accessory factors, help to generate an invaginated bud at the cell membrane,. One of these …

A protein with an apparent mol. wt of 18,000 daltons (synaptobrevin) was identified in
synaptic vesicles from rat brain. Some of its properties were studied using monoclonal and …