Background Reliable data on the prevalence and predictors of post-stroke dementia are
needed to inform patients and carers, plan services and clinical trials, ascertain the overall …

Background Daily aspirin reduces the long-term risk of death due to cancer. However, the
short-term effect is less certain, especially in women, effects on cancer incidence are largely …

Background Stroke is often preceded by transient ischaemic attack (TIA), but studies of
stroke risk after TIA are logistically difficult and have yielded conflicting results. However …

Stroke has multiple etiologies, but the underlying genes and pathways are largely unknown.
We conducted a multiancestry genome-wide-association meta-analysis in 521,612 …

Background Endarterectomy reduces risk of stroke in certain patients with recently
symptomatic internal carotid stenosis. However, investigators have made different …

Background Malignant infarction of the middle cerebral artery (MCA) is associated with an
80% mortality rate. Non-randomised studies have suggested that decompressive surgery …

Background The mechanisms by which hypertension causes vascular events are unclear.
Guidelines for diagnosis and treatment focus only on underlying mean blood pressure. We …

Background The incidence of stroke is predicted to rise because of the rapidly ageing
population. However, over the past two decades, findings of randomised trials have …

Background We aimed to validate two similar existing prognostic scores for early risk of
stroke after transient ischaemic attack (TIA) and to derive and validate a unified score …

Background Carotid endarterectomy reduces the risk of stroke in patients with recently
symptomatic stenosis. Benefit depends on the degree of stenosis, and we aimed to see …