Current status of deep brain stimulation for obsessive-compulsive disorder: a clinical review of different targets

PP de Koning, M Figee, P van den Munckhof… - Current psychiatry …, 2011 - Springer
Obsessive-compulsive disorder (OCD) is a chronic psychiatric disorder that affects 2% of the
general population. Despite optimal cognitive-behavioral and pharmacologic therapy …

Subthalamic nucleus versus globus pallidus bilateral deep brain stimulation for advanced Parkinson's disease (NSTAPS study): a randomised controlled trial

VJJ Odekerken, T van Laar, MJ Staal, A Mosch… - The Lancet …, 2013 - thelancet.com
Summary Background Patients with advanced Parkinson's disease often have rapid swings
between mobility and immobility, and many respond unsatisfactorily to adjustments in …

Deep brain stimulation of the nucleus accumbens for treatment-refractory obsessive-compulsive disorder

D Denys, M Mantione, M Figee… - Archives of general …, 2010 - jamanetwork.com
Context Obsessive-compulsive disorder (OCD) is a chronic psychiatric disorder that affects
2% of the general population. Even when the best available treatments are applied …

Deep brain stimulation restores frontostriatal network activity in obsessive-compulsive disorder

M Figee, J Luigjes, R Smolders… - Nature …, 2013 - nature.com
Little is known about the underlying neural mechanism of deep brain stimulation (DBS). We
found that DBS targeted at the nucleus accumbens (NAc) normalized NAc activity, reduced …

[HTML][HTML] On the pathophysiology and treatment of akinetic mutism

H Arnts, WS van Erp, JCM Lavrijsen, S van Gaal… - Neuroscience & …, 2020 - Elsevier
Akinetic mutism (AM) is a rare neurological disorder characterized by the presence of an
intact level of consciousness and sensorimotor capacity, but with a simultaneous decrease …

Pitx3 is required for motor activity and for survival of a subset of midbrain dopaminergic neurons

P Van den Munckhof, KC Luk, L Ste-Marie… - 2003 - journals.biologists.com
Mesencephalic dopaminergic (MesDA) neurons play crucial roles in motor and behavioral
processes; their loss in Parkinson's disease (PD) results in striatal dopamine (DA) deficiency …

Deep brain stimulation of the ventral anterior limb of the internal capsule for treatment-resistant depression: a randomized clinical trial

IO Bergfeld, M Mantione, MLC Hoogendoorn… - JAMA …, 2016 - jamanetwork.com
Importance Patients with treatment-resistant depression (TRD) do not respond sufficiently to
several consecutive treatments for major depressive disorder. Deep brain stimulation (DBS) …

GPi vs STN deep brain stimulation for Parkinson disease: three-year follow-up

VJJ Odekerken, JA Boel, BA Schmand, RJ de Haan… - Neurology, 2016 - AAN Enterprises
Objective: To compare motor symptoms, cognition, mood, and behavior 3 years after deep
brain stimulation (DBS) of the globus pallidus pars interna (GPi) and subthalamic nucleus …

Directional steering: a novel approach to deep brain stimulation

MF Contarino, LJ Bour, R Verhagen, MAJ Lourens… - Neurology, 2014 - AAN Enterprises
Objective: The aim of this study was to investigate whether directional steering through a
novel 32-contact electrode is safe and can modulate the thresholds for beneficial and side …

[HTML][HTML] Long-term experience with intraoperative microrecording during DBS neurosurgery in STN and GPi

LJ Bour, MF Contarino, EMJ Foncke, RMA De Bie… - Acta …, 2010 - Springer
Background Intraoperative microelectrode recording (MER) for targeting during deep brain
stimulation (DBS) procedures has been evaluated over a period of 4 years, in 57 …