The evidence base for diagnosis and management of ALS is still weak, and curative therapy
is lacking. Nonetheless, early diagnosis and symptomatic therapy can profoundly influence …

Objective To undertake a systematic review and meta-analysis of studies that investigated
prognostic factors and survival in patients with progressive supranuclear palsy (PSP) and …

Background Palliative care is increasingly offered earlier in the cancer trajectory but rarely in
Idiopathic Parkinson's Disease (IPD), Progressive Supranuclear Palsy (PSP) or Multiple …

The identification of genetic and epigenetic factors that are associated with an increased risk
of developing amyotrophic lateral sclerosis (ALS), or that modify the age of onset or rate of …

The objective was to identify factors associated with decisions made by patients with
amyotrophic lateral sclerosis (ALS) to accept or decline non-invasive ventilation (NIV) and/or …

Background Amyotrophic lateral sclerosis (ALS) is a primary progressive neurodegenerative
disease characterised by neuronal loss of lower motor neurons (in the spinal cord and …

The Multidisciplinary Care Clinic: The Principles and an International Perspective Page 1 27
The Multidisciplinary Care Clinic: The Principles and an International Perspective Hiroshi …

NODDI is a multi-compartment model of diffusion MRI that overcomes some of the limitations
of DTI. Our aim was to assess whether voxelwise analysis of NODDI parameters could …

Background Neurite Orientation Dispersion and Density Imaging (NODDI) is an established
technique for estimating complexity of neuronal architecture. We used NODDI to …