User profiles for "author:R A Barker"
Roger A BarkerUniversity of Cambridge Verified email at cam.ac.uk Cited by 66137 |
Diagnostic criteria for mild cognitive impairment in Parkinson's disease: Movement Disorder Society Task Force guidelines
I Litvan, JG Goldman, AI Tröster… - Movement …, 2012 - Wiley Online Library
Mild cognitive impairment is common in nondemented Parkinson's disease (PD) patients
and may be a harbinger of dementia. In view of its importance, the Movement Disorder …
and may be a harbinger of dementia. In view of its importance, the Movement Disorder …
Neuropsychological and clinical heterogeneity of cognitive impairment and dementia in patients with Parkinson's disease
Cognitive impairment in patients with Parkinson's disease is gaining increased clinical
significance owing to the relative success of therapeutic approaches to the motor symptoms …
significance owing to the relative success of therapeutic approaches to the motor symptoms …
Evolution of cognitive dysfunction in an incident Parkinson's disease cohort
We have previously performed detailed clinical and neuropsychological assessments in a
community-based cohort of patients with newly diagnosed parkinsonism, and through …
community-based cohort of patients with newly diagnosed parkinsonism, and through …
A functional role for adult hippocampal neurogenesis in spatial pattern separation
CD Clelland, M Choi, C Romberg, GD Clemenson Jr… - Science, 2009 - science.org
The dentate gyrus (DG) of the mammalian hippocampus is hypothesized to mediate pattern
separation—the formation of distinct and orthogonal representations of mnemonic …
separation—the formation of distinct and orthogonal representations of mnemonic …
The distinct cognitive syndromes of Parkinson's disease: 5 year follow-up of the CamPaIGN cohort
CH Williams-Gray, JR Evans, A Goris, T Foltynie… - Brain, 2009 - academic.oup.com
Cognitive abnormalities are common in Parkinson's disease, with important social and
economic implications. Factors influencing their evolution remain unclear but are crucial to …
economic implications. Factors influencing their evolution remain unclear but are crucial to …
Enhanced or impaired cognitive function in Parkinson's disease as a function of dopaminergic medication and task demands
We investigated how dopamine (DA) systems contribute to cognitive performance in the
domain of learning and attentional flexibility by examining effects of withdrawing DA-ergic …
domain of learning and attentional flexibility by examining effects of withdrawing DA-ergic …
[HTML][HTML] Targeting huntingtin expression in patients with Huntington's disease
SJ Tabrizi, BR Leavitt… - … England Journal of …, 2019 - Mass Medical Soc
Background Huntington's disease is an autosomal-dominant neurodegenerative disease
caused by CAG trinucleotide repeat expansion in HTT, resulting in a mutant huntingtin …
caused by CAG trinucleotide repeat expansion in HTT, resulting in a mutant huntingtin …
[HTML][HTML] Molecular diversity of midbrain development in mouse, human, and stem cells
G La Manno, D Gyllborg, S Codeluppi, K Nishimura… - Cell, 2016 - Elsevier
Understanding human embryonic ventral midbrain is of major interest for Parkinson's
disease. However, the cell types, their gene expression dynamics, and their relationship to …
disease. However, the cell types, their gene expression dynamics, and their relationship to …
The cognitive ability of an incident cohort of Parkinson's patients in the UK. The CamPaIGN study
We have used multiple sources to identify a population‐representative cohort of newly
diagnosed patients with parkinsonism and Parkinson's disease in the UK over a 2‐year …
diagnosed patients with parkinsonism and Parkinson's disease in the UK over a 2‐year …
Cognitive impairments in early Parkinson's disease are accompanied by reductions in activity in frontostriatal neural circuitry
SJG Lewis, A Dove, TW Robbins… - Journal of …, 2003 - Soc Neuroscience
Studies in patients with Parkinson's disease (PD) suggest that the characteristic motor
symptoms of the disorder are frequently accompanied by impairments in cognition that are …
symptoms of the disorder are frequently accompanied by impairments in cognition that are …