The purpose of this study was to analyze the clinical aspects in 130 patients presenting
periodic lateralized epileptiform discharges (PLEDs) in their EEG and to compare these …

Background Real-world data of current antiepileptic drugs (AEDs) used to treat focal
seizures is of importance to understand the efficacy and safety outside of the clinical trial …

Objective This study investigated early, real‐world outcomes with cenobamate (CNB) in a
large series of patients with highly drug‐resistant epilepsy within a Spanish Expanded …

Objectives Evaluate long‐term effectiveness and tolerability of brivaracetam in clinical
practice in patients with focal epilepsy. Materials and Methods This was a multicenter …

Objective To assess the effectiveness and tolerability of perampanel (PER) monotherapy in
routine clinical practice for the treatment of focal onset and generalized tonic‐clonic seizures …

Background The choice of antiepileptic drug (AED) therapy in patients with brain tumor-
related epilepsy (BTRE) is complicated, and there are a lack of robust clinical trial data to …

Lacosamide is approved as adjunctive therapy for focal epilepsies. The number of
antiepileptic drugs (AEDs) tried is associated with prognosis. This multicenter, retrospective …

Results: After intravenous penicillin therapy, the size of these lesions diminished
dramatically. That regression correlated with improvement in neuropsychologic test and CSF …

Conclusions Anti-NMDA encephalitis is a treatable disorder and, sometimes, the first
evidence of an underlying neoplasia, which makes its early recognition and treatment …

Background and objectives Many patients with epilepsy are treated with antiepileptic drug
(AED) polytherapy. Several factors influence the choice of early add-on therapy, and …