The ankle joint is subjected to more weight-bearing force per square centimeter and is more
commonly injured than any other joint in the body, but the prevalence of symptomatic …

Understanding the aetiology of epilepsy is essential both for clinical management of patients
and for conducting neurobiological research that will direct future therapies. The aetiology of …

Historical epidemiological perspectives from past pandemics and recent neurobiological
evidence link infections and psychoses, leading to concerns that COVID-19 will present a …

Background Concerns regarding potential neurological complications of COVID-19 are
being increasingly reported, primarily in small series. Larger studies have been limited by …

Developmental and epileptic encephalopathy (DEE) is a group of conditions characterized
by the co-occurrence of epilepsy and intellectual disability (ID), typically with developmental …

Background The spectrum of neurological and psychiatric complications associated with
paediatric SARS-CoV-2 infection is poorly understood. We aimed to analyse the range and …

Progressive functional decline in the epilepsies is largely unexplained. We formed the
ENIGMA-Epilepsy consortium to understand factors that influence brain measures in …

Background Despite progress in understanding the genetics of rare epilepsies, the more
common epilepsies have proven less amenable to traditional gene-discovery analyses. We …

Epilepsy is increasingly conceptualized as a network disorder. In this cross-sectional mega-
analysis, we integrated neuroimaging and connectome analysis to identify network …

The epilepsies are commonly accompanied by widespread abnormalities in cerebral white
matter. ENIGMA-Epilepsy is a large quantitative brain imaging consortium, aggregating data …