Patients with spontaneous (non-traumatic) subarachnoid haemorrhage usually present first
to their general practitioner. As general practitioners may see only a few cases during their …

Background Corticosteroids and antiviral agents are widely used to treat the early stages of
idiopathic facial paralysis (ie, Bell's palsy), but their effectiveness is uncertain. Methods We …

Background Medical students perceive neurology to be a difficult subject, a phenomenon
described as “neurophobia”. Studies investigating student attitudes towards neurology have …

Rhabdomyolysis is the combination of symptoms (myalgia, weakness and muscle swelling)
and a substantial rise in serum creatine kinase (CK)> 50 000 IU/L; there are many causes …

Inhibition of leucocyte trafficking by antagonism of the alpha4 (α4)-integrin has now been
validated as a therapeutic approach for the treatment of inflammatory diseases such as …

Objective: To show the influence of variations in case mix on clinical outcome indicators for
patients admitted to hospital with acute stroke. Design:“Before and after” cohort study, with …

Synthesis and SAR of aminopyrimidines as novel c-Jun N-terminal kinase (JNK) inhibitors -
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A novel series of aminopyrimidine IKK2 inhibitors have been developed which show
excellent in vitro inhibition of this enzyme and good selectivity over the IKK1 isoform. The …

Synthesis of novel substituted isoquinolones - ScienceDirect Skip to main contentSkip to
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Synthesis and structure–activity relationships of guanine analogues as phosphodiesterase 7
(PDE7) inhibitors - ScienceDirect Skip to main contentSkip to article Elsevier logo Journals & …