User profiles for "author:Ruben Smith"
Ruben SmithLund University Verified email at med.lu.se Cited by 9300 |
The pregnancy risk assessment monitoring system (PRAMS): overview of design and methodology
HB Shulman, DV D'Angelo… - … journal of public …, 2018 - ajph.aphapublications.org
Data System. The Pregnancy Risk Assessment Monitoring System (PRAMS) is an ongoing
state-based surveillance system of maternal behaviors, attitudes, and experiences before …
state-based surveillance system of maternal behaviors, attitudes, and experiences before …
Synaptic dysfunction in Huntington's disease: a new perspective
Huntington's disease (HD) is caused by a polyglutamine expansion in the protein huntingtin
and is characterized by intraneuronal inclusions and widespread neuronal death at the late …
and is characterized by intraneuronal inclusions and widespread neuronal death at the late …
Discriminative accuracy of plasma phospho-tau217 for Alzheimer disease vs other neurodegenerative disorders
Importance There are limitations in current diagnostic testing approaches for Alzheimer
disease (AD). Objective To examine plasma tau phosphorylated at threonine 217 (P-tau217) …
disease (AD). Objective To examine plasma tau phosphorylated at threonine 217 (P-tau217) …
Four distinct trajectories of tau deposition identified in Alzheimer's disease
Alzheimer's disease (AD) is characterized by the spread of tau pathology throughout the
cerebral cortex. This spreading pattern was thought to be fairly consistent across individuals …
cerebral cortex. This spreading pattern was thought to be fairly consistent across individuals …
Plasma P-tau181 in Alzheimer's disease: relationship to other biomarkers, differential diagnosis, neuropathology and longitudinal progression to Alzheimer's dementia
Plasma phosphorylated tau181 (P-tau181) might be increased in Alzheimer's disease (AD),
but its usefulness for differential diagnosis and prognosis is unclear. We studied plasma P …
but its usefulness for differential diagnosis and prognosis is unclear. We studied plasma P …
[HTML][HTML] Amyloid and tau PET-positive cognitively unimpaired individuals are at high risk for future cognitive decline
A major unanswered question in the dementia field is whether cognitively unimpaired
individuals who harbor both Alzheimer's disease neuropathological hallmarks (that is …
individuals who harbor both Alzheimer's disease neuropathological hallmarks (that is …
Plasma GFAP is an early marker of amyloid-β but not tau pathology in Alzheimer's disease
Although recent clinical trials targeting amyloid-β in Alzheimer's disease have shown
promising results, there is increasing evidence suggesting that understanding alternative …
promising results, there is increasing evidence suggesting that understanding alternative …
Accuracy of tau positron emission tomography as a prognostic marker in preclinical and prodromal Alzheimer disease: a head-to-head comparison against amyloid …
Importance Tau positron emission tomography (PET) tracers have proven useful for the
differential diagnosis of dementia, but their utility for predicting cognitive change is unclear …
differential diagnosis of dementia, but their utility for predicting cognitive change is unclear …
Discriminative accuracy of [18F] flortaucipir positron emission tomography for Alzheimer disease vs other neurodegenerative disorders
Importance The positron emission tomography (PET) tracer [18 F] flortaucipir allows in vivo
quantification of paired helical filament tau, a core neuropathological feature of Alzheimer …
quantification of paired helical filament tau, a core neuropathological feature of Alzheimer …
Associations of plasma phospho-tau217 levels with tau positron emission tomography in early Alzheimer disease
Importance There is an urgent need for inexpensive and minimally invasive blood
biomarkers for Alzheimer disease (AD) that could be used to detect early disease changes …
biomarkers for Alzheimer disease (AD) that could be used to detect early disease changes …