Pain and functional limitation are frequent in symptomatic tendinopathy. The essential lesion
of tendinopathy is a failed healing response. Understanding the cellular and molecular …

Nuclear factor κB (NF-κB) plays a pivotal role in inflammation, immunity, stress responses,
and protection from apoptosis. Canonical activation of NF-κB is dependent on the …

NF-κB is constitutively activated in primary human thyroid tumors, particularly in those of
anaplastic type. The inhibition of NF-κB activity in the human anaplastic thyroid carcinoma …

Abstract Context: Micro-RNAs (miRNAs) have been recently involved in the modulation of
several biological activities including cancer. Many human tumors show deregulated …

Autoantibodies against human thyroglobulin are a hallmark of autoimmune thyroid disease
in humans, and are often found in normal subjects. Their pathogenic significance is debated …

Thyroid cancer includes three types of carcinomas classified as differentiated thyroid
carcinomas (DTC), medullary thyroid carcinomas, and undifferentiated carcinomas (UTC) …

Retinoic acid-inducible gene-I (RIG-I) is a cytoplasmic immune receptor sensing viral RNA. It
triggers the release of type I interferons (IFN) and proinflammatory cytokines inducing an …

Oxidative stress caused by airway inflammation is increased in chronic obstructive
pulmonary disease (COPD) and may account for the progressive deterioration of structure …

The molecular basis for the DNA binding specificity of the thyroid transcription factor 1
homeodomain (TTF-1HD) has been investigated. Methylation and ethylation interference …

Cytoplasmic double-stranded RNA is sensed by RIG-I–like receptors (RLRs), leading to
induction of type I interferons (IFN-Is), proinflammatory cytokines, and apoptosis. Here, we …