Brain magnetic resonance imaging correlates of impaired cognition in patients with type 2 diabetes

SM Manschot, AMA Brands, J van der Grond… - Diabetes, 2006 - Am Diabetes Assoc
The structural correlates of impaired cognition in type 2 diabetes are unclear. The present
study compared cognition and brain magnetic resonance imaging (MRI) between type 2 …

Safety and efficacy of aspirin, unfractionated heparin, both, or neither during endovascular stroke treatment (MR CLEAN-MED): an open-label, multicentre …

…, MTB Truijman, S Zinkstok, PJ Koudstaal, S Manschot… - The Lancet, 2022 - thelancet.com
Background Aspirin and unfractionated heparin are often used during endovascular stroke
treatment to improve reperfusion and outcomes. However, the effects and risks of anti …

[HTML][HTML] Metabolic and vascular determinants of impaired cognitive performance and abnormalities on brain magnetic resonance imaging in patients with type 2 …

SM Manschot, GJ Biessels, H De Valk, A Algra… - Diabetologia, 2007 - Springer
Aims/hypothesis The determinants of cerebral complications of type 2 diabetes are unclear.
The present study aimed to identify metabolic and vascular factors that are associated with …

A detailed profile of cognitive dysfunction and its relation to psychological distress in patients with type 2 diabetes mellitus

AMA Brands, E Van den Berg, SM Manschot… - Journal of the …, 2007 - cambridge.org
Type 2 diabetes mellitus (DM2) is a common metabolic disorder. DM2 is associated with
cognitive impairments, and with depressive symptoms, which occur in about one third of …

Angiotensin converting enzyme inhibition partially prevents deficits in water maze performance, hippocampal synaptic plasticity and cerebral blood flow in …

SM Manschot, GJ Biessels, NE Cameron, MA Cotter… - Brain research, 2003 - Elsevier
Vascular dysfunction is important in the pathogenesis of peripheral complications of
diabetes. However, the effects of diabetes on cerebral blood flow and the role of vascular …

[HTML][HTML] Cerebral perfusion in relation to cognitive function and type 2 diabetes

AM Tiehuis, KL Vincken, E Van Den Berg, J Hendrikse… - Diabetologia, 2008 - Springer
Aim/hypothesis Underlying mechanisms for decreased cognitive functioning in patients with
type 2 diabetes are unclear. In the general population, cerebral hypoperfusion is a risk factor …

Mayo and NINDS scales for assessment of tendon reflexes: between observer agreement and implications for communication

S Manschot, L Van Passel, E Buskens… - Journal of Neurology …, 1998 - jnnp.bmj.com
The purpose of this study was to assess the between observer reliability of two standard
notation scales for grading tendon reflexes, The Mayo Clinic scale and the NINDS scale. In a …

Prehospital transdermal glyceryl trinitrate in patients with presumed acute stroke (MR ASAP): an ambulance-based, multicentre, randomised, open-label, blinded …

…, D Gerrits, J Coutinho, B Jansen, S Manschot… - The Lancet …, 2022 - thelancet.com
Background Pooled analyses of previous randomised studies have suggested that very
early treatment with glyceryl trinitrate (also known as nitroglycerin) improves functional …

Second IVIg Course in Guillain‐Barré Syndrome patients with poor prognosis (SID‐GBS trial): protocol for a double‐blind randomized, placebo‐controlled clinical trial

C Walgaard, BC Jacobs, HF Lingsma… - Journal of the …, 2018 - Wiley Online Library
One course of intravenous immunoglobulins (IVIg) of 2 g/kg is standard treatment in Guillain‐
Barré syndrome (GBS) patients unable to walk independently. Despite treatment some …

Second intravenous immunoglobulin dose in patients with Guillain-Barré syndrome with poor prognosis (SID-GBS): a double-blind, randomised, placebo-controlled …

C Walgaard, BC Jacobs, HF Lingsma… - The Lancet …, 2021 - thelancet.com
Background Treatment with one standard dose (2 g/kg) of intravenous immunoglobulin is
insufficient in a proportion of patients with severe Guillain-Barré syndrome. Worldwide …