Multiple sclerosis (MS) is a common, complex neurological disease. The precise aetiology of
MS is not yet known, although epidemiological data indicate that both genetic and …

Background Multiple sclerosis (MS) is a leading cause of disability in young adults.
Susceptibility to MS is determined by environmental exposure on the background of genetic …

Multiple sclerosis (MS) is a common, complex neurological disease. Epidemiological data
implicate both genetic and environmental factors in the etiology of MS, with various factors …

Background Incidence of multiple sclerosis is thought to be increasing, but this notion has
been difficult to substantiate. In a longitudinal population-based dataset of patients with …

Initially thought to play a restricted role in calcium homeostasis, the pleiotropic actions of
vitamin D in biology and their clinical significance are only now becoming apparent …

Multiple sclerosis (MS) is a complex trait in which allelic variation in the MHC class II region
exerts the single strongest effect on genetic risk. Epidemiological data in MS provide strong …

Background and objective: We explored which clinical and biochemical variables predict
conversion from clinically isolated syndrome (CIS) to clinically definite multiple sclerosis …

Background Multiple sclerosis (MS) appears to develop in genetically susceptible
individuals as a result of environmental exposures. Epstein-Barr virus (EBV) infection is an …

Vitamin D and its metabolites have pleomorphic roles in both nervous system health and
disease. Animal models have been paramount in contributing to our knowledge and …

Background Venous thromboembolism (VTE) is a common complication during and after a
hospital admission. Although it is mainly considered a complication of surgery, it often …