Abstract The Expanded Disability Status Scale (EDSS) is the current 'gold standard'for
monitoring disease severity in multiple sclerosis (MS). The EDSS is a physician-based …

Our ability to interact with those around us plays an important role in our relationships,
mental well being and ability to successfully navigate the complex social society in which we …

Abstract Myotonic Dystrophy type 1 (DM1) is an autosomal dominant condition caused by
expansion of the CTG triplet repeats within the myotonic dystrophy protein of the kinase …

The Optic Neuritis Treatment Trial previously reported that corticosteroids accelerated visual
recovery in optic neuritis (ON) without improving outcome. This finding related largely to …

Objectives Suboptimal bone health is increasingly recognised as an important cause of
morbidity. Multiple sclerosis (MS) has been consistently associated with an increased risk of …

Background Depression is a potentially treatable condition which can co-exist with multiple
sclerosis (MS). To date, the existing literature has not been collated in a systematic fashion …

Background There is an urgent clinical need for reliable remote monitoring methods in
Multiple Sclerosis (MS). We evaluated the use of remotely patient-recorded timed 25-foot …

Introduction This study compares the white matter lesion distribution and substrate between
patients with type one myotonic dystrophy (DM1) and patients with Multiple Sclerosis (MS) …

Objective We investigated whether computerised measurement of visuoperceptual deficits
can detect cognitive dysfunction in multiple sclerosis (MS). Methods We assessed people …

Background There is an urgent need for reliable methods to remotely monitor Multiple
Sclerosis (MS). Existing assessments, such as Timed 25-Foot Walk (T25FW) and 9-Hole …