Sepsis-associated encephalopathy (SAE) is a diffuse brain dysfunction that occurs
secondary to infection in the body without overt CNS infection. SAE is frequently …

We convened an international group of experts to standardize definitions of New‐Onset
Refractory Status Epilepticus (NORSE), Febrile Infection‐Related Epilepsy Syndrome …

Objectives To investigate the hypothesis that strokes occurring in patients with coronavirus
disease 2019 (COVID-19) have distinctive features, we investigated stroke risk, clinical …

Background: Hypoxia in tumors is associated with malignant progression, metastatic spread,
and increased resistance to radiotherapy and chemotherapy. Molecular O2 is required for …

Abstract This 2023 Clinical Practice Guideline provides the biomedical definition of death
based on permanent cessation of brain function that applies to all persons, as well as …

Primary tumors and metastatic involvement of the central nervous system (CNS) lead to a
multitude of symptoms and care needs. Patients and caregivers struggle with physical and …

New-onset refractory status epilepticus (NORSE) is a clinical presentation, not a specific
diagnosis, in a patient without active epilepsy or other preexisting relevant neurologic …

Multi-modal neuroimaging techniques have the potential to dramatically improve the
diagnosis of the level consciousness and prognostication of neurological outcome for …

Mefloquine, an antimalarial medication with efficacy against JC virus, was used to treat
progressive multifocal leukoencephalopathy. A 54-year-old woman with sarcoidosis …

Establishing when cerebral cortical activity stops relative to circulatory arrest during the
dying process will enhance trust in donation after circulatory determination of death. We …