Reactive oxygen species (ROS) are frequently produced during viral infections. Generation
of these ROS can be both beneficial and detrimental for many cellular functions. When …

The eukaryotic initiation factor eIF4G is a large modular protein which serves as a docking
site for initiation factors and proteins involved in RNA translation. Together with eIF4E and …

Some 20 years ago, the study of picornaviral RNA translation led to the characterization of
an alternative mechanism of initiation by direct ribosome binding to the 5′ UTR. By using a …

Here, we have characterized a step in translation initiation of viral and cellular mRNAs that
contain RNA secondary structures immediately at the vicinity of their m7GTP cap. This is …

Abstract The World Health Organization conservatively estimates that 80 million people
suffer from infertility worldwide. Male factors are believed to be responsible for 20–50% of all …

Programmable nucleases have enabled rapid and accessible genome engineering in
eukaryotic cells and living organisms. However, their delivery into target cells can be …

We studied the degree of dependence on vision, for postural control and for perception,
among male adult dancers and untrained subjects. First, body sways were analyzed on a …

The 5′ leader of the human immunodeficiency virus type 1 (HIV-1) genomic RNA contains
highly structured domains involved in key steps of the viral life cycle. These RNA domains …

The foot and mouth disease virus, a picornavirus, encodes two forms of a cysteine
proteinase (leader or L protease) that bisects the EIF4G polypeptide of the initiation factor …

Ribosomal RNAs (rRNAs) are main effectors of messenger RNA (mRNA) decoding, peptide-
bond formation, and ribosome dynamics during translation. Ribose 2′-O-methylation (2 …