Connectivity predicts deep brain stimulation outcome in P arkinson disease

A Horn, M Reich, J Vorwerk, N Li, G Wenzel… - Annals of …, 2017 - Wiley Online Library
Objective The benefit of deep brain stimulation (DBS) for Parkinson disease (PD) may
depend on connectivity between the stimulation site and other brain regions, but which …

[HTML][HTML] Accuracy and reliability of the kinect version 2 for clinical measurement of motor function

K Otte, B Kayser, S Mansow-Model, J Verrel, F Paul… - PloS one, 2016 - journals.plos.org
Background The introduction of low cost optical 3D motion tracking sensors provides new
options for effective quantification of motor dysfunction. Objective The present study aimed to …

Long-term disease progression in spinocerebellar ataxia types 1, 2, 3, and 6: a longitudinal cohort study

H Jacobi, ST du Montcel, P Bauer, P Giunti… - The Lancet …, 2015 - thelancet.com
Background Spinocerebellar ataxias are dominantly inherited neurodegenerative diseases.
As potential treatments for these diseases are being developed, precise knowledge of their …

Reliability and validity of the scale for the assessment and rating of ataxia: a study in 64 ataxia patients

A Weyer, M Abele, T Schmitz‐Hübsch… - … : official journal of the …, 2007 - Wiley Online Library
The objective of this study was to test the reliability and validity of the Scale for the
Assessment and Rating of Ataxia (SARA) in ataxia patients not suffering from autosomal …

The natural history of spinocerebellar ataxia type 1, 2, 3, and 6: a 2-year follow-up study

H Jacobi, P Bauer, P Giunti, R Labrum, MG Sweeney… - Neurology, 2011 - AAN Enterprises
Objective: To obtain quantitative data on the progression of the most common
spinocerebellar ataxias (SCAs) and identify factors that influence their progression, we …

Reliability and validity of the International Cooperative Ataxia Rating Scale: a study in 156 spinocerebellar ataxia patients

T Schmitz‐Hübsch… - … : official journal of the …, 2006 - Wiley Online Library
To evaluate the efficacy of treatments in spinocerebellar ataxias (SCAs), appropriate clinical
scales are required. This study evaluated metric properties of the International Cooperative …

Visualization, quantification and correlation of brain atrophy with clinical symptoms in spinocerebellar ataxia types 1, 3 and 6

JB Schulz, J Borkert, S Wolf, T Schmitz-Hübsch… - Neuroimage, 2010 - Elsevier
BACKGROUND AND OBJECTIVE: Biomarkers to monitor neurological dysfunction in
autosomal dominant inherited spinocerebellar ataxias (SCA) are lacking. We therefore …

Bright light therapy in Parkinson's disease: a pilot study

S Paus, T Schmitz‐Hübsch, U Wüllner… - … : official journal of the …, 2007 - Wiley Online Library
Several observations suggest a beneficial effect of melatonin antagonism for Parkinson's
disease (PD). Although bright light therapy (BLT) suppresses melatonin release and is an …

Comparison of three clinical rating scales in Friedreich ataxia (FRDA)

K Bürk, U Mälzig, S Wolf, S Heck… - Movement …, 2009 - Wiley Online Library
To test the validity and reliability of the scale for the assessment and rating of ataxia (SARA)
in Friedreich ataxia (FRDA). SARA is limited to eight items and can be performed rapidly …

[HTML][HTML] Neuropsychological features of patients with spinocerebellar ataxia (SCA) types 1, 2, 3, and 6

I Klinke, M Minnerop, T Schmitz-Hübsch, M Hendriks… - The cerebellum, 2010 - Springer
A subtype-specific impairment of cognitive functions in spinocerebellar ataxia (SCA) patients
is still debated. Thirty-two SCA patients (SCA1, 6; SC2, 3; SCA3, 15; SCA6, 8) and 14 …