Summary The 2015 Magnetic Resonance Imaging in Multiple Sclerosis and 2016
Consortium of Multiple Sclerosis Centres guidelines on the use of MRI in diagnosis and …

The role of MRI in the assessment of multiple sclerosis (MS) goes far beyond the diagnostic
process. MRI techniques can be used as regular monitoring to help stage patients with MS …

The clinical use of MRI in patients with multiple sclerosis (MS) has advanced markedly over
the past few years. Technical improvements and continuously emerging data from clinical …

Background Progressive multifocal leukoencephalopathy (PML) was reported to have
developed in three patients treated with natalizumab. We conducted an evaluation to …

Background Oral fumarate (BG00012) might have dual anti-inflammatory and
neuroprotective effects. Our aim was to assess the efficacy and safety of BG00012 in …

Functional magnetic resonance imaging blood-oxygenation-level-dependent (BOLD) signal
increases (activations) and BOLD signal decreases (“deactivations”) were compared in six …

MRI has improved the diagnostic work-up of multiple sclerosis, but inappropriate image
interpretation and application of MRI diagnostic criteria contribute to misdiagnosis. Some …

Background and Purpose—An increased frequency of clinically silent microbleeds (MB) has
recently been observed in patients with sporadic small-vessel disease related to vascular …

Background A substantial impediment to progress in trials of new therapies in
neuromuscular disorders is the absence of responsive outcome measures that correlate with …

Unfixed and fixed postmortem multiple sclerosis (MS) brain is being used to probe pathology
underlying quantitative MR (qMR) changes. Effects of fixation on qMR indices in MS brain …