Mice lacking the vitamin D receptor exhibit impaired bone formation, uterine hypoplasia and growth retardation after weaning

T Yoshizawa, Y Handa, Y Uematsu, S Takeda… - Nature …, 1997 - nature.com
Abstract 1α, 25-Dihydroxy vitamin D3 [1α, 25 (OH) 2D3] an active form of vitamin D, has
roles in many biological phenomena such as calcium homeostasis and bone formation1–3 …

TGF-β-related mechanisms of bone destruction in multiple myeloma

T Matsumoto, M Abe - Bone, 2011 - Elsevier
In destructive bone lesions of multiple myeloma (MM), osteoclastic bone resorption is
enhanced, while bone formation is suppressed with impaired osteoblast differentiation from …

The infrared astronomical mission AKARI

H Murakami, H Baba, P Barthel… - Publications of the …, 2007 - academic.oup.com
AKARI, the first Japanese satellite dedicated to infrared astronomy, was launched on 2006
February 21, and started observations in May of the same year. AKARI has a 68.5 cm cooled …

Bright organic electroluminescent devices having a metal-doped electron-injecting layer

J Kido, T Matsumoto - Applied Physics Letters, 1998 - pubs.aip.org
Bright organic electroluminescent devices were developed using a metal-doped organic
layer as an electron-injecting layer at the interface between the cathode and the emitter …

Sclerostin: from bench to bedside

S Tanaka, T Matsumoto - Journal of bone and mineral metabolism, 2021 - Springer
Skeletal integrity is maintained by a meticulous balance between bone resorption and bone
formation, and recent studies have revealed the essential role of canonical Wnt signaling …

[HTML][HTML] Transforming Growth Factor-β1 as a Common Target Molecule for Development of Cardiovascular Diseases, Renal Insufficiency and Metabolic Syndrome

K Aihara, Y Ikeda, S Yagi, M Akaike… - … research and practice, 2011 - hindawi.com
Transforming growth factor-β1 (TGF-β1) is a polypeptide member of the transforming growth
factor β superfamily of cytokines. It is a secreted protein that performs many cellular functions …

Deletion of vitamin D receptor gene in mice results in abnormal skeletal muscle development with deregulated expression of myoregulatory transcription factors

I Endo, D Inoue, T Mitsui, Y Umaki, M Akaike… - …, 2003 - academic.oup.com
Although rachitic/osteomalacic myopathy caused by impaired vitamin D actions has long
been described, the molecular pathogenesis remains elusive. To determine physiological …

The Infrared Camera (IRC) for AKARI–Design and imaging performance

T Onaka, H Matsuhara, T Wada… - Publications of the …, 2007 - academic.oup.com
Abstract The Infrared Camera (IRC) is one of two focal-plane instruments on the AKARI
satellite. It is designed for wide-field deep imaging and low-resolution spectroscopy in the …

Osteoclasts enhance myeloma cell growth and survival via cell-cell contact: a vicious cycle between bone destruction and myeloma expansion

M Abe, K Hiura, J Wilde, A Shioyasono, K Moriyama… - Blood, 2004 - ashpublications.org
Multiple myeloma (MM) expands in the bone marrow and causes devastating bone
destruction by enhancing osteoclastic bone resorption in its vicinity, suggesting a close …

Myeloma cells suppress bone formation by secreting a soluble Wnt inhibitor, sFRP-2

T Oshima, M Abe, J Asano, T Hara, K Kitazoe… - Blood, 2005 - ashpublications.org
Multiple myeloma (MM) develops devastating bone destruction with enhanced bone
resorption and suppressed bone formation. In contrast to enhanced osteoclastogenesis, little …