User profiles for "author:Tracy R Melzer"
Tracy R MelzerUniversity of Otago, New Zealand Brain Research Institute Verified email at nzbri.org Cited by 4667 |
The genetic architecture of the human cerebral cortex
KL Grasby, N Jahanshad, JN Painter, L Colodro-Conde… - Science, 2020 - science.org
INTRODUCTION The cerebral cortex underlies our complex cognitive capabilities.
Variations in human cortical surface area and thickness are associated with neurological …
Variations in human cortical surface area and thickness are associated with neurological …
Disparities in the pace of biological aging among midlife adults of the same chronological age have implications for future frailty risk and policy
Some humans age faster than others. Variation in biological aging can be measured in
midlife, but the implications of this variation are poorly understood. We tested associations …
midlife, but the implications of this variation are poorly understood. We tested associations …
Grey matter atrophy in cognitively impaired Parkinson's disease
Objective Mild cognitive impairment and dementia are common non-motor features of
Parkinson's disease (PD). The aim of this study was to characterise grey matter changes …
Parkinson's disease (PD). The aim of this study was to characterise grey matter changes …
[HTML][HTML] General functional connectivity: Shared features of resting-state and task fMRI drive reliable and heritable individual differences in functional brain networks
Intrinsic connectivity, measured using resting-state fMRI, has emerged as a fundamental tool
in the study of the human brain. However, due to practical limitations, many studies do not …
in the study of the human brain. However, due to practical limitations, many studies do not …
Arterial spin labelling reveals an abnormal cerebral perfusion pattern in Parkinson's disease
There is a need for objective imaging markers of Parkinson's disease status and
progression. Positron emission tomography and single photon emission computed …
progression. Positron emission tomography and single photon emission computed …
[HTML][HTML] Brain-age in midlife is associated with accelerated biological aging and cognitive decline in a longitudinal birth cohort
ML Elliott, DW Belsky, AR Knodt, D Ireland… - Molecular …, 2021 - nature.com
An individual's brainAGE is the difference between chronological age and age predicted
from machine-learning models of brain-imaging data. BrainAGE has been proposed as a …
from machine-learning models of brain-imaging data. BrainAGE has been proposed as a …
White matter microstructure deteriorates across cognitive stages in Parkinson disease
Objectives: To characterize different stages of Parkinson disease (PD)-related cognitive
decline using diffusion tensor imaging (DTI) and investigate potential relationships between …
decline using diffusion tensor imaging (DTI) and investigate potential relationships between …
Characterizing mild cognitive impairment in Parkinson's disease
JC Dalrymple‐Alford, L Livingston… - Movement …, 2011 - Wiley Online Library
There is growing interest in identifying Parkinson's disease (PD) patients with mild cognitive
impairment (PD‐MCI), but widely disparate criteria have been used. We assessed 143 PD …
impairment (PD‐MCI), but widely disparate criteria have been used. We assessed 143 PD …
International multicenter analysis of brain structure across clinical stages of Parkinson's disease
MA Laansma, JK Bright, S Al‐Bachari… - Movement …, 2021 - Wiley Online Library
Background Brain structure abnormalities throughout the course of Parkinson's disease
have yet to be fully elucidated. Objective Using a multicenter approach and harmonized …
have yet to be fully elucidated. Objective Using a multicenter approach and harmonized …
Reduced grey matter perfusion without volume loss in early relapsing-remitting multiple sclerosis
L Debernard, TR Melzer, S Van Stockum… - Journal of Neurology …, 2014 - jnnp.bmj.com
Background Grey matter (GM) pathology in multiple sclerosis (MS) is associated with
progressive long-term disability. Detection of GM abnormalities in early MS may therefore be …
progressive long-term disability. Detection of GM abnormalities in early MS may therefore be …