Longitudinal relationship between hearing aid use and cognitive function in older Americans

A Maharani, P Dawes, J Nazroo… - Journal of the …, 2018 - Wiley Online Library
Objectives To test whether hearing aid use alters cognitive trajectories in older adults.
Design US population‐based longitudinal cohort study Setting Data were drawn from the …

Association of retinal neurodegeneration on optical coherence tomography with dementia: a population-based study

U Mutlu, JM Colijn, MA Ikram… - JAMA …, 2018 - jamanetwork.com
Importance Retinal structures may serve as a biomarker for dementia, but longitudinal
studies examining this link are lacking. Objective To investigate the association of inner …

Retinal neurodegeneration and brain MRI markers: the Rotterdam Study

U Mutlu, PWM Bonnemaijer, MA Ikram, JM Colijn… - Neurobiology of …, 2017 - Elsevier
We investigated the association of specific retinal sublayer thicknesses on optical coherence
tomography (OCT) with brain magnetic resonance imaging (MRI) markers. We included …

Lifetime risk of common neurological diseases in the elderly population

S Licher, SKL Darweesh, FJ Wolters, L Fani… - Journal of Neurology …, 2019 - jnnp.bmj.com
Objective To quantify the burden of common neurological disease in older adults in terms of
lifetime risks, including their co-occurrence and preventive potential, within a competing risk …

Retinal microvasculature is associated with long-term survival in the general adult Dutch population

U Mutlu, MK Ikram, FJ Wolters, A Hofman… - …, 2016 - Am Heart Assoc
Retinal vascular diameters are associated with (sub) clinical cardiovascular disease and
short-term cardiovascular mortality, but their association with long-term mortality is uncertain …

Psoriasis is not associated with cognition, brain imaging markers, and risk for dementia: the Rotterdam Study

E Pezzolo, U Mutlu, MW Vernooij… - Journal of the American …, 2021 - Elsevier
Background Based on increased cardiometabolic comorbidities, inflammation, and an
overlap in genetics with Alzheimer disease, psoriasis patients might be at risk for cognitive …

Thinner retinal layers are associated with changes in the visual pathway: A population‐based study

U Mutlu, MK Ikram, GV Roshchupkin… - Human brain …, 2018 - Wiley Online Library
Increasing evidence shows that thinner retinal nerve fiber layer (RNFL) and ganglion cell
layer (GCL), assessed on optical coherence tomography (OCT), are reflecting global brain …

[HTML][HTML] Vitamin D and retinal microvascular damage: The Rotterdam Study

U Mutlu, MA Ikram, A Hofman, PTVM de Jong… - Medicine, 2016 - journals.lww.com
Vitamin D has been linked to various cardiovascular risk factors including indices of large-
vessel disease. However, it remains unclear whether vitamin D is also associated with …

Retinal microvasculature and white matter microstructure: The Rotterdam Study

U Mutlu, LGM Cremers, M De Groot, A Hofman… - Neurology, 2016 - AAN Enterprises
Objective: To investigate whether retinal microvascular damage is related to normal-
appearing white matter microstructure on diffusion tensor MRI. Methods: We included 2,436 …

A systematic review and participant-level meta-analysis found little association of retinal microvascular caliber with reduced kidney function

WK Lye, E Paterson, CC Patterson, AP Maxwell… - Kidney international, 2021 - Elsevier
Previously, variation in retinal vascular caliber has been reported in association with chronic
kidney disease (CKD) but findings remain inconsistent. To help clarify this we conducted …