Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis

…, S Männistö, CP Manrique, R Martin, V Martinelli… - Nature …, 2013 - nature.com
Using the ImmunoChip custom genotyping array, we analyzed 14,498 subjects with multiple
sclerosis and 24,091 healthy controls for 161,311 autosomal variants and identified 135 …

Late onset multiple sclerosis: clinical characteristics, prognostic factors and differential diagnosis

V Martinelli, M Rodegher, L Moiola, G Comi - Neurological Sciences, 2004 - Springer
Late onset multiple sclerosis (LOMS), defined as the first presentation of clinical symptoms in
patients over 50, is not a rare phenomenon as previously thought, since the prevalence …

Effect of early interferon treatment on conversion to definite multiple sclerosis: a randomised study

…, P Seeldrayers, PS Sørensen, M Rovaris, V Martinelli… - The Lancet, 2001 - thelancet.com
Background Interferon beta reduces activity in multiple sclerosis as measured clinically and
by magnetic resonance imaging (MRI). We assessed the effect of interferon beta-1a on the …

Effect of glatiramer acetate on conversion to clinically definite multiple sclerosis in patients with clinically isolated syndrome (PreCISe study): a randomised, double …

G Comi, V Martinelli, M Rodegher, L Moiola… - The Lancet, 2009 - thelancet.com
Background Glatiramer acetate, approved for the treatment of relapsing-remitting multiple
sclerosis, reduces relapses and disease activity and burden monitored by MRI. We …

Mitoxantrone: benefits and risks in multiple sclerosis patients

V Martinelli, M Radaelli, L Straffi, M Rodegher… - Neurological …, 2009 - Springer
Mitoxantrone (MTX) is a synthetic antineoplastic cytotoxic drug, active both on proliferative
and non-proliferative cells. The efficacy of MTX has been suggested by many open-label or …

[HTML][HTML] Psychological and psychopathological aspects of kidney transplantation: a systematic review

…, G Biffa, N Bennardi, P Zoncheddu, V Martinelli… - Frontiers in …, 2020 - frontiersin.org
Kidney transplantation is a serious event that involves profound psychological, relational
and social changes both for the patient and his family context. Assessment of personality …

Evidence for widespread axonal damage at the earliest clinical stage of multiple sclerosis

…, O Gonen, C Kesavadas, A Ghezzi, V Martinelli… - Brain, 2003 - academic.oup.com
Although axonal pathology is recognized as one of the major pathological features of
multiple sclerosis, it is less clear how early in its course it occurs and how it correlates with …

A magnetization transfer imaging study of normal-appearing white matter in multiple sclerosis

M Filippi, A Campi, V Dousset, C Baratti, V Martinelli… - Neurology, 1995 - AAN Enterprises
Article abstract-We attempted to define the role of subtle changes in the normal-appearing
white matter (NAWM) in the development of disability in multiple sclerosis (MS). Twenty …

The prevalence of pain in multiple sclerosis: a multicenter cross-sectional study

…, G D'aleo, C Gasperini, A Ghezzi, V Martinelli… - Neurology, 2004 - AAN Enterprises
In a multicenter cross-sectional study, the authors assessed pain in patients with multiple
sclerosis (MS) using a symptom-oriented approach. Out of 2,077 questionnaires, we used …

Conversion from clinically isolated syndrome to multiple sclerosis: a large multicentre study

…, L Kappos, R Furlan, V Martinelli… - Multiple Sclerosis …, 2015 - journals.sagepub.com
Background and objective: We explored which clinical and biochemical variables predict
conversion from clinically isolated syndrome (CIS) to clinically definite multiple sclerosis …