Treatment-resistant schizophrenia: treatment response and resistance in psychosis (TRRIP) working group consensus guidelines on diagnosis and terminology
OD Howes, R McCutcheon, O Agid… - American Journal of …, 2017 - Am Psychiatric Assoc
Objective: Research and clinical translation in schizophrenia is limited by inconsistent
definitions of treatment resistance and response. To address this issue, the authors …
definitions of treatment resistance and response. To address this issue, the authors …
The need for speed: an update on methamphetamine addiction
AM Barr, WJ Panenka, GW MacEwan… - Journal of psychiatry and …, 2006 - jpn.ca
The psychostimulant methamphetamine (MA) is a highly addictive drug that has surged in
popularity over the last decade in North America. A burgeoning number of clandestine drug …
popularity over the last decade in North America. A burgeoning number of clandestine drug …
Methamphetamine use: a comprehensive review of molecular, preclinical and clinical findings
WJ Panenka, RM Procyshyn, T Lecomte… - Drug and alcohol …, 2013 - Elsevier
Methamphetamine (MA) is a highly addictive psychostimulant drug that principally affects the
monoamine neurotransmitter systems of the brain and results in feelings of alertness …
monoamine neurotransmitter systems of the brain and results in feelings of alertness …
Hippocampal plasticity in response to exercise in schizophrenia
FG Pajonk, T Wobrock, O Gruber… - Archives of general …, 2010 - jamanetwork.com
Context Hippocampal volume is lower than expected in patients with schizophrenia;
however, whether this represents a fixed deficit is uncertain. Exercise is a stimulus to …
however, whether this represents a fixed deficit is uncertain. Exercise is a stimulus to …
Location of a major susceptibility locus for familial schizophrenia on chromosome 1q21-q22
LM Brzustowicz, KA Hodgkinson, EWC Chow… - Science, 2000 - science.org
Schizophrenia is a complex disorder, and there is substantial evidence supporting a genetic
etiology. Despite this, prior attempts to localize susceptibility loci have produced …
etiology. Despite this, prior attempts to localize susceptibility loci have produced …
Decreased concentrations of GLUT1 and GLUT3 glucose transporters in the brains of patients with Alzheimer's disease
IA Simpson, KR Chundu, T Davies‐Hill… - Annals of Neurology …, 1994 - Wiley Online Library
Glucose metabolism is depressed in the temporal and parietal regions of the cortex in
patients with Alzheimer's disease. We measured the concentrations of two glucose …
patients with Alzheimer's disease. We measured the concentrations of two glucose …
[PDF][PDF] Human hippocampal neurogenesis persists in aged adults and Alzheimer's disease patients
Whether hippocampal neurogenesis persists throughout life in the human brain is not fully
resolved. Here, we demonstrate that hippocampal neurogenesis is persistent through the …
resolved. Here, we demonstrate that hippocampal neurogenesis is persistent through the …
[HTML][HTML] Clozapine alone versus clozapine and risperidone with refractory schizophrenia
WG Honer, AE Thornton, EYH Chen… - … England Journal of …, 2006 - Mass Medical Soc
Background The treatment of schizophrenia with multiple antipsychotic drugs is common,
but the benefits and risks are not known. Methods In a randomized, double-blind study, we …
but the benefits and risks are not known. Methods In a randomized, double-blind study, we …
Much of late life cognitive decline is not due to common neurodegenerative pathologies
Objective The pathologic indices of Alzheimer disease, cerebrovascular disease, and Lewy
body disease accumulate in the brains of older persons with and without dementia, but the …
body disease accumulate in the brains of older persons with and without dementia, but the …
[HTML][HTML] SNAP-25 is a promising novel cerebrospinal fluid biomarker for synapse degeneration in Alzheimer's disease
A Brinkmalm, G Brinkmalm, WG Honer, L Frölich… - Molecular …, 2014 - Springer
Background Synaptic degeneration is an early pathogenic event in Alzheimer's disease,
associated with cognitive impairment and disease progression. Cerebrospinal fluid …
associated with cognitive impairment and disease progression. Cerebrospinal fluid …