The aim of this work was to add to the body of data on the frequency and severity of
degenerative radiographic findings at adjacent levels after anterior cervical interbody fusion …

Objective: To determine the surgery-related and hardware-related complications of deep-
brain stimulation (DBS) at a single centre. Methods: 262 consecutive patients (472 …

Recent progress in scientific and clinical research has made gene therapy a promising
option for efficient and targeted treatment of several inherited and acquired disorders. One of …

Adult stem cells are promising cellular vehicles for therapy of malignant gliomas as they
have the ability to migrate into these tumors and even track infiltrating tumor cells. However …

Neuroimaging techniques represent powerful tools to assess disease-specific cellular,
biochemical and molecular processes non-invasively in vivo. Besides providing precise …

Background Inhibition of the epidermal growth factor receptor (EGFR) has shown clinical
success in patients with advanced non-small cell lung cancer (NSCLC). Somatic mutations …

OBJECTIVE: In patients in very poor neurological condition (World Federation of
Neurosurgical Societies Grade V) with aneurysmal subarachnoid hemorrhage, early surgery …

For clinical application of stem cell–based therapies, noninvasive detection of applied stem
cells is of high importance. We report on the feasibility of detecting implanted neural …

The hypothesis of this study was that distinct experimental glioblastoma phenotypes
resembling human disease can be noninvasively distinguished at various disease stages by …

To further develop gene therapy for patients with glioblastomas, an experimental gene
therapy protocol was established comprising a series of imaging parameters for (i) …