Cerebral autosomal recessive arteriopathy with subcortical infarcts and
leukoencephalopathy (CARASIL) is clinically characterized by early-onset dementia, stroke …

Background A long non-coding RNA (lncRNA), nuclear-enriched abundant transcript 1_2
(NEAT1_2), constitutes nuclear bodies known as “paraspeckles”. Mutations of RNA binding …

TAR DNA-binding protein-43 (TDP-43) has been recently identified as a major component of
the ubiquitinated inclusions found in frontotemporal lobar degeneration with ubiquitin …

Amyotrophic lateral sclerosis (ALS) is a representative neurological disease that is known to
devastate entire motor neurons within a period of just a few years. Discoveries of the specific …

Amyotrophic lateral sclerosis (ALS) is a late-onset motor neuron disorder. Although its
neuropathology is well understood, the cellular and molecular mechanisms are yet to be …

Musashi1 (MSI1) is an RNA-binding protein that plays critical roles in nervous-system
development and stem-cell self-renewal. Here, we examined its role in the progression of …

Objectives: The objective of this study was to clarify the characteristic brain MRI findings for
genetically diagnosed CARASIL (cerebral autosomal recessive arteriopathy with subcortical …

The Musashi (Msi) family is a group of RNA-binding proteins characterized by two RNA
recognition motifs (RRMs) and is evolutionarily conserved [1, 2]. In mammals, two isoforms …

To establish highly precise patterns of neural connectivity, developing axons must stop
growing at their appropriate destinations and specifically synapse with target cells. However …

Objective This study aimed to identify associations between multimorbidity and subjective
health outcomes among the very old persons, after adjusting for coexisting conditions such …