User profiles for "author:Zhihui Deng"

Zhihui Deng

Associate Professor of Medicine, McMaster University
Verified email at medportal.ca
Cited by 172

COMMD1 is linked to the WASH complex and regulates endosomal trafficking of the copper transporter ATP7A

CA Phillips-Krawczak, A Singla… - Molecular biology of …, 2015 - Am Soc Cell Biol
COMMD1 deficiency results in defective copper homeostasis, but the mechanism for this has
remained elusive. Here we report that COMMD1 is directly linked to early endosomes …

Folate intake and risk of colorectal cancer: a systematic review and up-to-date meta-analysis of prospective studies

H Fu, J He, C Li, Z Deng, H Chang - European Journal of Cancer …, 2023 - journals.lww.com
Purpose Colorectal cancer is one of the most commonly diagnosed and deadly cancers
worldwide. Epidemiological studies on the relationship between folate intake and the risk of …

[HTML][HTML] Structural and mechanistic insights into regulation of the retromer coat by TBC1d5

D Jia, JS Zhang, F Li, J Wang, Z Deng, MA White… - Nature …, 2016 - nature.com
Retromer is a membrane coat complex that is recruited to endosomes by the small GTPase
Rab7 and sorting nexin 3. The timing of this interaction and consequent endosomal …

Expression of postsynaptic Ca2+‐activated K+ (SK) channels at C‐bouton synapses in mammalian lumbar α‐motoneurons

AS Deardorff, SH Romer, Z Deng… - The Journal of …, 2013 - Wiley Online Library
Key points Spinal cord α‐motoneurons display strong membrane immunoreactivity (IR)
against small‐conductance calcium‐activated potassium channel (SK) isoform SK2, and a …

HLA class II allele DRB1* 16: 02 is associated with anti-NMDAR encephalitis

Y Shu, W Qiu, J Zheng, X Sun, J Yin, X Yang… - Journal of Neurology …, 2019 - jnnp.bmj.com
Background and objective Aetiology and pathogenesis of anti-N-methyl-D-aspartate
receptor (anti-NMDAR) encephalitis, the most common autoimmune encephalitis, is largely …

Theaflavin alleviates oxidative injury and atherosclerosis progress via activating microRNA‐24‐mediated Nrf2/HO‐1 signal

J Zeng, Z Deng, Y Zou, C Liu, H Fu, Y Gu… - Phytotherapy …, 2021 - Wiley Online Library
Theaflavin (TF) in black tea has been shown to have significant antioxidant and anti‐
inflammatory capacity; however, the effects and the underlying mechanism of TF on …

[HTML][HTML] m6A methyltransferase METTL3 reduces hippocampal neuron apoptosis in a mouse model of autism through the MALAT1/SFRP2/Wnt/β-catenin axis

Y Ming, Z Deng, X Tian, Y Jia, M Ning… - Psychiatry …, 2022 - ncbi.nlm.nih.gov
Objective Hippocampal neuron apoptosis contributes to autism, while METTL3 has been
documented to possess great potentials in neuron apoptosis. Our study probed into the role …

Purification and characterization of a novel fibrinolytic enzyme from the polychaete, Neanthes japonica (Iznka)

Z Deng, S Wang, Q Li, X Ji, L Zhang, M Hong - Bioresource technology, 2010 - Elsevier
A novel fibrinolytic enzyme from Neanthes japonica (Iznka), named NJF, was purified to
electrophoretic homogeneity using ammonium sulfate precipitation, hydrophobic interaction …

Corrosion-induced growth control of lead halide perovskite nanoparticles

C Sun, K Lian, X Zhang, Z Wang, Y Zhao… - Chemical Engineering …, 2024 - Elsevier
Abstract Ultrasmall CsPbBr 3 perovskite nanoparticles (NPs) have gained great attention as
a potential blue-cyan emissive material due to their strong quantum confinement effects …

[PDF][PDF] The molecular origin and consequences of escape from miRNA regulation by HLA-C alleles

C O'huigin, S Kulkarni, Y Xu, Z Deng, J Kidd… - The American Journal of …, 2011 - cell.com
Differential expression of human leukocyte antigen C (HLA-C) allotypes is mediated by the
binding of a microRNA, miR-148a, to the 3′ untranslated region of some, but not all, HLA-C …