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We report here an uncommon case of amyloid myopathy presenting with atrophic proximal muscle weakness. The patient had an IgGκ monoclonal gammopathy and plasmacytosis in the bone marrow. Some of the clinical features of the disorder are highlighted in the present case.
A 57 year old man presented with decreased appetite for seven months, difficulty in getting up from a sitting position for three months, and oedema of his feet for two days. He had particular difficulty in getting up in an Indian toilet. He was not a known diabetic or hypertensive and did not smoke or drink alcohol. On examination, there was wasting of shoulder girdle muscles—deltoid, supraspinatus, infraspinatus, pectorals, rhomboids, and biceps with grade III (MRC) power (fig 1). There was also wasting and weakness of pelvic girdle muscles and glutei with grade IV (MRC) power. Deep reflexes were present and sensations were intact. Plantar flexor reflexes were normal.
There were …