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Coexisting vertical and horizontal one and a half syndromes
  1. S TERAO,
  2. Y OSANO,
  3. T FUKUOKA,
  4. N MIURA,
  5. T MITSUMA
  1. (died 10 February 2000)
  2. Division of Neurology, Fourth Department of Internal Medicine, Aichi Medical University, Nagakute, Aichi 480–1195, Japan
  3. Department of Neurology, Nagoya University School of Medicine, Nagoya, Japan
  1. Dr Shin-ichi Terao 102949{at}gk.amu.aichi-med-u.ac.jp
  1. G SOBUE
  1. (died 10 February 2000)
  2. Division of Neurology, Fourth Department of Internal Medicine, Aichi Medical University, Nagakute, Aichi 480–1195, Japan
  3. Department of Neurology, Nagoya University School of Medicine, Nagoya, Japan
  1. Dr Shin-ichi Terao 102949{at}gk.amu.aichi-med-u.ac.jp

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Supranuclear ocular movements comprise chiefly vertical and horizontal movements; horizontal movements are controlled by the subcortical centres located mainly at the pontine level and vertical movements at the level of the rostral midbrain.1 2 The classic one and a half syndrome is produced by a unilateral pontine tegmental lesion that includes the paramedian pontine reticular formation and medial longitudinal fasciculus on the same side, and has been considered an important ocular sign in neurological diagnosis.1 3 4 Vertical, as distinct from horizontal, one and a half syndrome, has also been documented recently.1 2 5 6 We report on a patient with concurrent vertical and horizontal one and a half syndromes.

A 57 year old man was admitted to hospital with a sudden onset of dysarthria and loss of consciousness while playing golf. He had a history of aortic regurgitation and heart failure 8 years previously, and underwent aortic valve replacement 5 years previously, when he started to take oral antiplatelet and anticoagulant drugs. On admission, he was comatose, and his blood pressure was 140/76 mm Hg. He also had atrial fibrillation, Cheyne-Stokes respiration, bilateral miosis, and a positive Babinski's sign. Brain CT showed lesions suspected of being infarcts in the right medial thalamus …

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